CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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GD7360000
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CHEMICAL NAME :
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Cinnamamide, N-(2-hydroxyethyl)-
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CAS REGISTRY NUMBER :
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6961-46-2
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LAST UPDATED :
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199201
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DATA ITEMS CITED :
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4
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MOLECULAR FORMULA :
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C11-H13-N-O2
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MOLECULAR WEIGHT :
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191.25
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WISWESSER LINE NOTATION :
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Q2MV1U1R
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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>3 gm/kg
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TOXIC EFFECTS :
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Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness Behavioral - irritability
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REFERENCE :
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EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 9,205,1974
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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>400 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 28,28,1985
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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2950 mg/kg
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TOXIC EFFECTS :
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Behavioral - changes in motor activity (specific assay) Behavioral - muscle weakness Behavioral - irritability
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REFERENCE :
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EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 9,205,1974
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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>150 mg/kg
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TOXIC EFFECTS :
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Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness Behavioral - irritability
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REFERENCE :
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EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 9,205,1974
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