80734-02-7

80734-02-7 structure

Name: Lenampicillin hydrochloride
Chemical Name: (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate,hydrochloride
CAS Number: 80734-02-7
Molecular Formula: C₂₁H₂₄ClN₃O₇S
Molecular Weight: 497.95
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2018-06-05 08:00:00
Modify Date: 2025-08-25 18:30:00
Lenampicillin (hydrochloride) is the efficient prodrug of ampicillin (ABPC ) in terms of the enhancement of absorption and decrease of side effects.In vivo : The intestinal absorption of LAPC is satisfactory in view of the urinary excretion of metabolites, accounting for 93% of dose in human, 74% in dogs and 55% in rats, respectively.

Name	(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate,hydrochloride
Synonyms	lenampicillin hydrochloride Lenampicillin hydrochloride (JP16) Valacillin (TN) Lenampicillin (hydrochloride)

Description	Lenampicillin (hydrochloride) is the efficient prodrug of ampicillin (ABPC ) in terms of the enhancement of absorption and decrease of side effects.In vivo : The intestinal absorption of LAPC is satisfactory in view of the urinary excretion of metabolites, accounting for 93% of dose in human, 74% in dogs and 55% in rats, respectively.
Related Catalog	Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Cancer
References	[1]. Awata N et al. [Metabolism of lenampicillin hydrochloride. II. Metabolism of promoiety]. Jpn J Antibiot. 1985 Jul;38(7):1785-93. [2]. Awata N et al. [Metabolism of lenampicillin hydrochloride. I. Metabolism of ampicillin structure]. Jpn J Antibiot. 1985 Jul;38(7):1776-84.

80715-31-7

40966-78-7

~75%

80734-02-7

Literature: Chemical and Pharmaceutical Bulletin, , vol. 32, # 11 p. 4316 - 4322

37830-90-3

80734-02-7

Literature: Chemical and Pharmaceutical Bulletin, , vol. 32, # 6 p. 2241 - 2248

80715-22-6

80734-02-7

Literature: Chemical and Pharmaceutical Bulletin, , vol. 32, # 6 p. 2241 - 2248

Precursor 4
80715-31-7 40966-78-7 37830-90-3 80715-22-6
DownStream 0