Lenampicillin hydrochloride

Modify Date: 2025-08-25 18:30:00

Lenampicillin hydrochloride Structure
Lenampicillin hydrochloride structure
Common Name Lenampicillin hydrochloride
CAS Number 80734-02-7 Molecular Weight 497.95
Density N/A Boiling Point 717.4ºC at 760 mmHg
Molecular Formula C21H24ClN3O7S Melting Point N/A
MSDS N/A Flash Point 387.7ºC

 Use of Lenampicillin hydrochloride


Lenampicillin (hydrochloride) is the efficient prodrug of ampicillin (ABPC ) in terms of the enhancement of absorption and decrease of side effects.In vivo : The intestinal absorption of LAPC is satisfactory in view of the urinary excretion of metabolites, accounting for 93% of dose in human, 74% in dogs and 55% in rats, respectively.

 Names

Name (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate,hydrochloride
Synonym More Synonyms

 Lenampicillin hydrochloride Biological Activity

Description Lenampicillin (hydrochloride) is the efficient prodrug of ampicillin (ABPC ) in terms of the enhancement of absorption and decrease of side effects.In vivo : The intestinal absorption of LAPC is satisfactory in view of the urinary excretion of metabolites, accounting for 93% of dose in human, 74% in dogs and 55% in rats, respectively.
Related Catalog
References

[1]. Awata N et al. [Metabolism of lenampicillin hydrochloride. II. Metabolism of promoiety]. Jpn J Antibiot. 1985 Jul;38(7):1785-93.

[2]. Awata N et al. [Metabolism of lenampicillin hydrochloride. I. Metabolism of ampicillin structure]. Jpn J Antibiot. 1985 Jul;38(7):1776-84.

 Chemical & Physical Properties

Boiling Point 717.4ºC at 760 mmHg
Molecular Formula C21H24ClN3O7S
Molecular Weight 497.95
Flash Point 387.7ºC
PSA 170.38000
LogP 1.86060
Storage condition 2-8℃

 Synonyms

lenampicillin hydrochloride
Lenampicillin hydrochloride (JP16)
Valacillin (TN)
Lenampicillin (hydrochloride)
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