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Product Name: 1,2,2-Trichloro-1,1-difluoro-ethane
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354-21-2

354-21-2 structure

354-21-2 structure

Name: 1,2,2-Trichloro-1,1-difluoroethane
Chemical Name: 1,1-Difluoro-1,2,2-trichloroethane
CAS Number: 354-21-2
Molecular Formula: C₂HCl₃F₂
Molecular Weight: 169.385
Catalog: Organic raw materials Organic fluorine compound Fluoroethane series
Create Date: 2018-12-21 18:13:19
Modify Date: 2025-08-25 13:41:31

Name	1,1-Difluoro-1,2,2-trichloroethane
Synonyms	1,2,2-Trichloro-1,1-difluoroethane 1,1-difluoro-1,2,2-trichloroethane hcfc-122 EINECS 206-548-9 Ethane, 1,2,2-trichloro-1,1-difluoro- r122 1,2,2-trichloro-1,1-difluoro-ethane MFCD00039339

Density	1.6±0.1 g/cm3
Boiling Point	74.8±8.0 °C at 760 mmHg
Melting Point	-141ºC
Molecular Formula	C₂HCl₃F₂
Molecular Weight	169.385
Flash Point	-4.3±11.9 °C
Exact Mass	167.911194
LogP	2.30
Vapour Pressure	118.5±0.1 mmHg at 25°C
Index of Refraction	1.403

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KI1435000

CHEMICAL NAME :: Ethane, 1,1-difluoro-1,2,2-trichloro-

CAS REGISTRY NUMBER :: 354-21-2

BEILSTEIN REFERENCE NO. :: 1736764

LAST UPDATED :: 199710

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C2-H-Cl3-F2

MOLECULAR WEIGHT :: 169.38

WISWESSER LINE NOTATION :: GYGXGFF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 7500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: HXPHAU Handbuch der Experimentellen Pharmakologie. (Berlin, Ger.) New series: V.1-49, 1935-78. For publisher information, see HEPHD2. Volume(issue)/page/year: 20(Pt 1),459,1966

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4000 ppm/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: UCMH** Union Carbide Manual Hazard Sheet. (Industrial Medicine & Toxicology Dept., Union Carbide Corp., 270 Park Ave., New York, NY 10017) Volume(issue)/page/year: 15NOV1962 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 110 ppm/6H/2W-I

TOXIC EFFECTS :: Liver - changes in liver weight Kidney, Ureter, Bladder - other changes in urine composition Biochemical - Metabolism (Intermediary) - lipids including transport

REFERENCE :: INHTE5 Inhalation Toxicology. (Hemisphere Publishing Corp., c/o Taylor & Francis Inc., 1900 Frost Rd., Suite 101, Bristol, PA 19007) V.1- 1989- Volume(issue)/page/year: 4,81,1992

Hazard Codes	Xi: Irritant;F: Flammable;
Risk Phrases	R59
Safety Phrases	59
RIDADR	UN 3082
HS Code	2903791090

Precursor 10
127-18-4 7783-71-3 75-68-3 75-37-6
359-29-5 116-14-3 76-01-7 79719-21-4
76-13-1 354-14-3
DownStream 10
306-83-2 354-24-5 359-10-4 685-21-2
79-35-6 79-01-6 21400-41-9 76-01-7
67-72-1 29185-18-0

HS Code	2903791090
Summary	2903791090 halogenated derivatives of methane, ethane or propane (hcfcs)only with fluorine and chlorine。supervision conditions:14xy(import license,export license,export license,export license)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:5.5%。general tariff:30.0%

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