Name | 2-chloro-3,5-dinitropyridine |
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Synonyms |
2-Chloro-3,5-dinitropyridine
MFCD00006233 EINECS 219-937-3 2-Chlor-3,5-dinitro-pyridin Pyridine,2-chloro-3,5-dinitro 2-Chloro3,5-dinitropyridine Pyridine, 2-chloro-3,5-dinitro- 3,5-dinitro-2-chloropyridine |
Density | 1.7±0.1 g/cm3 |
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Boiling Point | 320.9±37.0 °C at 760 mmHg |
Melting Point | 63-65 °C(lit.) |
Molecular Formula | C5H2ClN3O4 |
Molecular Weight | 203.540 |
Flash Point | 147.9±26.5 °C |
Exact Mass | 202.973389 |
PSA | 104.53000 |
LogP | 0.86 |
Vapour Pressure | 0.0±0.7 mmHg at 25°C |
Index of Refraction | 1.635 |
Storage condition | 2-8°C |
Synonym:None Known Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: 36/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
Irritating to eyes and skin. Potential Health Effects Eye: Causes eye irritation. May cause chemical conjunctivitis. Skin: Causes skin irritation. Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause cardiac disturbances. May cause central nervous system depression. May be harmful if swallowed. Inhalation: May cause respiratory tract irritation. May cause cardiac abnormalities. Can produce delayed pulmonary edema. Inhalation at high concentrations may cause CNS depression and asphixiation. Chronic: Effects may be delayed. Section 4 - FIRST AID MEASURES Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Ingestion: Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Inhalation: Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Containers may explode when heated. Non-combustible, substance itself does not burn but may decompose upon heating to produce irritating, corrosive and/or toxic fumes. Runoff from fire control or dilution water may cause pollution. Extinguishing Media: Use water spray to cool fire-exposed containers. For small fires, use dry chemical, carbon dioxide, or water spray. For large fires, use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions. Provide ventilation. Section 7 - HANDLING and STORAGE Handling: Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Wash clothing before reuse. Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep refrigerated. (Store below 4C/39F.) Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 2578-45-2: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: slightly yellow Odor: None reported. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 64.00 - 66.00 deg C Autoignition Temperature: Not applicable. Flash Point: Not applicable. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C5H2ClN3O4 Molecular Weight: 203.54 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable at room temperature in closed containers under normal storage and handling conditions. Conditions to Avoid: Incompatible materials, dust generation, excess heat, strong oxidants. Incompatibilities with Other Materials: Oxidizing agents. Hazardous Decomposition Products: Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen. Hazardous Polymerization: Has not been reported. Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 2578-45-2: US6504750 LD50/LC50: CAS# 2578-45-2: Dermal, guinea pig: LD50 = >1 gm/kg; Oral, mouse: LD50 = 50 mg/kg; Oral, rat: LD50 = 50 mg/kg. Carcinogenicity: 2-Chloro-3,5-Dinitropyridine - Not listed by ACGIH, IARC, or NTP. Other: See actual entry in RTECS for complete information. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Shipping Name: TOXIC SOLID, ORGANIC, N.O.S.* Hazard Class: 6.1 UN Number: 2811 Packing Group: III IMO Shipping Name: TOXIC SOLID, ORGANIC, N.O.S. Hazard Class: 6.1 UN Number: 2811 Packing Group: III RID/ADR Shipping Name: TOXIC SOLID, ORGANIC, N.O.S. Hazard Class: 6.1 UN Number: 2811 Packing group: III Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XI Risk Phrases: R 36/38 Irritating to eyes and skin. Safety Phrases: S 28A After contact with skin, wash immediately with plenty of water. WGK (Water Danger/Protection) CAS# 2578-45-2: No information available. Canada CAS# 2578-45-2 is listed on Canada's NDSL List. CAS# 2578-45-2 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 2578-45-2 is listed on the TSCA inventory. SECTION 16 - ADDITIONAL INFORMATION N/A |
Symbol |
GHS06 |
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Signal Word | Danger |
Hazard Statements | H300 |
Precautionary Statements | P264-P301 + P310 |
Personal Protective Equipment | Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges |
Hazard Codes | T: Toxic;Xi: Irritant; |
Risk Phrases | R25 |
Safety Phrases | S26-S36/37/39-S45 |
RIDADR | UN 2811 6.1/PG 2 |
WGK Germany | 3 |
RTECS | US6504750 |
Packaging Group | II |
Hazard Class | 6.1 |
~94% 2578-45-2 |
Literature: Rasheed, Khalid; Warkentin, James D. Journal of Heterocyclic Chemistry, 1981 , vol. 18, p. 1581 - 1585 |
~% 2578-45-2 |
Literature: Journal of the Chemical Society, , p. 2590,2593 |
~% 2578-45-2 |
Literature: Journal of the Chemical Society, , p. 2590,2593 |
Precursor 3 | |
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DownStream 10 | |