19083-00-2

19083-00-2 structure

Name: gracillin
Chemical Name: Gracillin
CAS Number: 19083-00-2
Molecular Formula: C₄₅H₇₂O₁₇
Molecular Weight: 885.043
Catalog: Biochemical Plant extracts
Create Date: 2018-06-30 12:14:22
Modify Date: 2024-01-02 18:35:04
Gracillin is a kind of steroidal saponin isolated from the root bark of wild yam Dioscorea nipponica with antitumor agent.Gracillin could induce cell cycle arrest, oxidative stress, and apoptosis in HL60 cells.[1]

Name	Gracillin
Synonyms	β-D-Glucopyranoside, (3β,25R)-spirost-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1->2)-O-[β-D-glucopyranosyl-(1->3)]- (3β,25R)-Spirost-5-en-3-yl 6-deoxy-α-L-mannopyranosyl-(1->2)-[β-D-glucopyranosyl-(1->3)]-β-D-glucopyranoside

Description	Gracillin is a kind of steroidal saponin isolated from the root bark of wild yam Dioscorea nipponica with antitumor agent.Gracillin could induce cell cycle arrest, oxidative stress, and apoptosis in HL60 cells.[1]
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Cancer Natural Products >> Terpenoids and Glycosides
References	[1]. Chen CR et al. Gracillin induces apoptosis in HL60 human leukemic cell line via oxidative stress and cell cycle arrest of G1. Pharmazie. 2015 Mar;70(3):199-204.