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5579-66-8

5579-66-8 structure
5579-66-8 structure
  • Name: Decaethylene glycol
  • Chemical Name: decaethylene glycol
  • CAS Number: 5579-66-8
  • Molecular Formula: C20H42O11
  • Molecular Weight: 458.541
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-08-17 09:36:31
  • Modify Date: 2024-01-02 18:51:59
  • Decaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name decaethylene glycol
Synonyms 3,6,9,12,15,18,21,24,27-Nonaoxanonacosane-1,29-diol
2-[2-[2-[2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
EINECS 226-962-3
Decaethylene Glycol
Description Decaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.1±0.1 g/cm3
Boiling Point 539.5±45.0 °C at 760 mmHg
Melting Point 28ºC
Molecular Formula C20H42O11
Molecular Weight 458.541
Flash Point 280.1±28.7 °C
Exact Mass 458.272705
PSA 123.53000
LogP -4.38
Vapour Pressure 0.0±3.3 mmHg at 25°C
Index of Refraction 1.464
HS Code 2909499000
Precursor  0

DownStream  4

HS Code 2909499000
Summary 2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%