Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 1-Phenyl-2,5,8,11,14,17,20,23,26,29-decaoxahentriacontan-31-ol
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Huang

DC Chemicals Limited
China
Product Name: Benzyl-PEG10-alcohol
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

908258-44-6

908258-44-6 structure

908258-44-6 structure

Name: Benzyl-PEG10-alcohol
Chemical Name: 2-[2-[2-[2-[2-[2-[2-[2-[2-(2-phenylmethoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
CAS Number: 908258-44-6
Molecular Formula: C₂₇H₄₈O₁₁
Molecular Weight: 548.66300
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2017-01-14 07:08:48
Modify Date: 2024-01-02 17:26:50
Benzyl-PEG10-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	2-[2-[2-[2-[2-[2-[2-[2-[2-(2-phenylmethoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
Synonyms	decaethylene glycol monobenzyl ether 1-Phenyl-2,5,8,11,14,17,20,23,26,29-decaoxahentriacontan-31-ol

Description	Benzyl-PEG10-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₇H₄₈O₁₁
Molecular Weight	548.66300
Exact Mass	548.32000
PSA	112.53000
LogP	1.34490

5579-66-8 structure

5579-66-8

100-39-0 structure

100-39-0

~%

908258-44-6 structure

908258-44-6

Literature: CHUGAI SEIYAKU KABUSHIKI KAISHA Patent: EP1854792 A1, 2007 ; Location in patent: Page/Page column 207-208 ;

Precursor 2
5579-66-8 100-39-0
DownStream 0