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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: N6-Methyladenosine
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1867-73-8

1867-73-8 structure

1867-73-8 structure

Name: N6-Methyladenosine
Chemical Name: N6-methyladenosine
CAS Number: 1867-73-8
Molecular Formula: C₁₁H₁₅N₅O₄
Molecular Weight: 281.26800
Catalog: Research Areas Others
Create Date: 2018-06-11 09:37:23
Modify Date: 2026-07-06 10:12:02
N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes.

Name	N6-methyladenosine
Synonyms	6-Methylaminopurinosine Adenosine, N-methyl (2R,3S,4R,5R)-2-(HydroxyMethyl)-5-(6-(MethylaMino)-9H-purin-9-yl)tetrahydrofuran-3,4-diol N6-Methyladenosine , Modified adenosine analog RNA-modified nucleoside m6A 6-Methylaminopurine ribonucleoside 6-METHYLAMINOPURINE 9-RIBOFURANOSIDE N-Methyladenosine N6-methyladenosine, 10 mM in DMSO 6-methylaminopurine riboside N-6-methyladenosine,inhibit,N6-Methyladenosine,Inhibitor,Endogenous Metabolite,N6methyladenosine,N6 methyladenosine,Influenza Virus N6-Me N6-Me-A 6-N-Methyladenoside 2-(hydroxymethyl)-5-(6-(methylamino)-9H-purin-9-yl)tetrahydrofuran-3,4-diol n6-methyladenosine NSC-29409 N(6)-methyladenosine 6-Methylaminopurine D-riboside Adenosine,N-methyl N6-Me-Adenosine Adenosine Impurity 15 N6-Methyladenosine RNA-modified nucleoside m6A N6-Me-rA N6,N6-Methyladenosin (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-methylaminopurin-9-yl)oxolane-3,4-diol

Description	N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes.
Related Catalog	Signaling Pathways >> Others >> Others Natural Products >> Alkaloid Research Areas >> Others
In Vitro	N6-methyladenosine (m6A) is selectively recognized by the human YTH domain family 2 (YTHDF2) protein to regulate mRNA degradation. N6-methyladenosine (m6A), a prevalent internal modification in the messenger RNA of all eukaryotes, is post-transcriptionally installed by m6A methyltransferase (e.g., MT-A70) within the consensus sequence of G(m6A)C (70%) or A(m6A)C (30%). N6-methyladenosine (m6A)-containing RNAs are greatly enriched in the YTHDF-bound portion and diminished in the flow-through portion[1]. N6-methyladenosine (m6A), the most abundant internal RNA modification, functions in diverse biological processes, including regulation of embryonic stem cell self-renewal and differentiation. N6-methyladenosine (m6A) is a large protein complex, consisting in part of methyltransferase-like 3 (METTL3) and methyltransferase-like 14 (METTL14) catalytic subunits[2].
References	[1]. Wang X, et al. N6-methyladenosine-dependent regulation of messenger RNA stability. Nature. 2014 Jan 2;505(7481):117-20. [2]. Li Y, et al. Genome-wide detection of high abundance N6-methyladenosine sites by microarray. RNA. 2015 Aug;21(8):1511-8.

Density	1.85g/cm3
Boiling Point	649.1ºC at 760mmHg
Molecular Formula	C₁₁H₁₅N₅O₄
Molecular Weight	281.26800
Flash Point	346.3ºC
Exact Mass	281.11200
PSA	125.55000
Vapour Pressure	9.86E-18mmHg at 25°C
Index of Refraction	1.814
Storage condition	2-8°C

Hazard Codes	Xi
HS Code	2934999090

Precursor 9
74465-47-7 74-89-5 2004-06-0 17331-15-6
52376-60-0 71118-24-6 593-51-1 56787-20-3
4566-77-2
DownStream 1
443-72-1

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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