187949-02-6
187949-02-6 structure
- Name: Albaconazole
- Chemical Name: 7-chloro-3-[(2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1,2,4-triazol-1-yl)butan-2-yl]quinazolin-4-one
- CAS Number: 187949-02-6
- Molecular Formula: C20H16ClF2N5O2
- Molecular Weight: 431.823
- Create Date: 2018-06-19 11:45:03
- Modify Date: 2024-01-07 22:37:51
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Albaconazole, also known as UR-9825; W-0027, is a 14alpha-Demethylase inhibitor potentially for the treatment of fungal infection.
| Name | 7-chloro-3-[(2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1,2,4-triazol-1-yl)butan-2-yl]quinazolin-4-one |
|---|---|
| Synonyms |
albacolazole
7-Chloro-3-[(2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)-2-butanyl]-4(3H)-quinazolinone (1R,2R)-7-chloro-3-[2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]quinazolin-4(3H)-one UNII-YDW24Y8IAB Albaconazole UR 9825 Albaconazole [INN] (1R,2R)-7-chloro-3-[2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]quinazilin-4(3H)-one Albaconazol 4(3H)-Quinazolinone, 7-chloro-3-[(1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]- 7-chloro-3-((1r,2r)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1h-1,2,4-triazol-1-yl)propyl)quinazolin-4(3h)-one |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 658.9±65.0 °C at 760 mmHg |
| Melting Point | 124-126°C |
| Molecular Formula | C20H16ClF2N5O2 |
| Molecular Weight | 431.823 |
| Flash Point | 352.3±34.3 °C |
| Exact Mass | 431.096069 |
| PSA | 85.83000 |
| LogP | 3.00 |
| Vapour Pressure | 0.0±2.1 mmHg at 25°C |
| Index of Refraction | 1.667 |
| Storage condition | -20°C Freezer |
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187949-02-6 |
| Literature: Journal of Medicinal Chemistry, , vol. 41, # 11 p. 1869 - 1882 |
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187949-02-6 |
| Literature: Journal of Medicinal Chemistry, , vol. 41, # 11 p. 1869 - 1882 |
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187949-02-6 |
| Literature: Journal of Medicinal Chemistry, , vol. 41, # 11 p. 1869 - 1882 |
| Precursor 3 | |
|---|---|
| DownStream 0 | |