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60784-43-2

60784-43-2 structure
60784-43-2 structure
  • Name: 1,1′-TETRAMETHYLENEBIS(3-(2-CHLORO-ETHYL)-3-NITROSOUREA)
  • Chemical Name: 1-(2-chloroethyl)-3-[4-[[2-chloroethyl(nitroso)carbamoyl]amino]butyl]-1-nitrosourea
  • CAS Number: 60784-43-2
  • Molecular Formula: C10H18Cl2N6O4
  • Molecular Weight: 357.19400
  • Create Date: 2016-08-23 15:57:11
  • Modify Date: 2024-01-11 17:40:44

Name 1-(2-chloroethyl)-3-[4-[[2-chloroethyl(nitroso)carbamoyl]amino]butyl]-1-nitrosourea
Synonyms wln: onn2gvm4mvnno&2g
Density 1.47g/cm3
Molecular Formula C10H18Cl2N6O4
Molecular Weight 357.19400
Exact Mass 356.07700
PSA 123.54000
LogP 2.41200
Index of Refraction 1.587

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YU2640000
CHEMICAL NAME :
Urea, 1,1'-tetramethylenebis(3-(2-chloroethyl)-3-nitroso-
CAS REGISTRY NUMBER :
60784-43-2
LAST UPDATED :
199612
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C10-H18-Cl2-N6-O4
MOLECULAR WEIGHT :
357.24
WISWESSER LINE NOTATION :
ONN2GVM4MVNNO&2G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
46 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - acute pulmonary edema Liver - hepatitis (hepatocellular necrosis), diffuse Blood - changes in bone marrow (not otherwise specified)
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
Sex chromosome loss and nondisjunction

MUTATION DATA

TYPE OF TEST :
Gene conversion and mitotic recombination
TEST SYSTEM :
Yeast - Saccharomyces cerevisiae
DOSE/DURATION :
500 umol/L/16H
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 42,45,1977