1079-02-3

1079-02-3 structure

Name: (2H5)Benzoic acid
Chemical Name: benzoic acid-d5
CAS Number: 1079-02-3
Molecular Formula: C₇HD₅O₂
Molecular Weight: 127.152
Catalog: Chemical reagent Deuterated reagent
Create Date: 2018-02-14 08:00:00
Modify Date: 2024-01-06 21:58:32
Benzoic acid-d5 is a deuterium substitute for Benzoic acid. Benzoic acid is an aromatic alcohol that occurs naturally in many plants and is a common additive in food, beverages, cosmetics and other products. Benzoic acid can act as a preservative by inhibiting bacteria and fungi[1][2].

Name	benzoic acid-d5
Synonyms	Benzoic-d acid pentadeuterated benzoic acid (H)Benzoic acid Benzoic-d5 acid MFCD00002400 1,2,3,4,5-pentadeuteriobenzoic acid EINECS 214-089-0 2,3,4,5,6-pentadeuteriobenzoic acid ring deuterated benzoic acid d5-benzoic acid

Description	Benzoic acid-d5 is a deuterium substitute for Benzoic acid. Benzoic acid is an aromatic alcohol that occurs naturally in many plants and is a common additive in food, beverages, cosmetics and other products. Benzoic acid can act as a preservative by inhibiting bacteria and fungi[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. Benzoic acid-d5 can be used for labeling and quantifying the glycopeptides of human serum IgG (hIgG)[3].
References	[1]. Edward M Russak, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. doi: 10.1177/1060028018797110. Epub 2018 Aug 23. [2]. Nair B, et al. Final report on the safety assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate. Int J Toxicol. 2001;20 Suppl 3:23-50. [3]. Masaki Kurogochi, et al. Relative quantitation of glycopeptides based on stable isotope labeling using MALDI-TOF MS. Molecules. 2014 Jul 9;19(7):9944-61.

Symbol	GHS05, GHS07, GHS08
Signal Word	Danger
Hazard Statements	H302-H315-H317-H318-H334-H335
Precautionary Statements	P261-P280-P305 + P351 + P338-P342 + P311
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes	Xn
Risk Phrases	R22
Safety Phrases	S22-S26-S36
WGK Germany	3