Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 1'-hydroxy Bufuralol
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

DC Chemicals Limited
China
Product Name: 1'-Hydroxy bufuralol
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

57704-16-2

57704-16-2 structure

57704-16-2 structure

Name: 4-amino-5-(methoxycarbonyl)thiophene-2-carboxylic acid
Chemical Name: 1'-Hydroxy Bufuralol
CAS Number: 57704-16-2
Molecular Formula: C₁₆H₂₃NO₃
Molecular Weight: 277.35900
Catalog: Research Areas Metabolic Disease
Create Date: 2018-09-19 19:12:54
Modify Date: 2024-01-02 18:21:52
1'-Hydroxy bufuralol, the main metabolite of bufuralol, can reflect CYP2D activity[1].

Name	1'-Hydroxy Bufuralol
Synonyms	2-(tert-butylamino)-1-[7-(1-hydroxyethyl)-1-benzofuran-2-yl]ethanol 4-amino-5-(methoxycarbonyl)thiophene-2-carboxylic acid

Description	1'-Hydroxy bufuralol, the main metabolite of bufuralol, can reflect CYP2D activity[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
References	[1]. Evangelos P Daskalopoulos, et al. D₂-dopaminergic receptor-linked pathways: critical regulators of CYP3A, CYP2C, and CYP2D. Mol Pharmacol. 2012 Oct;82(4):668-78. [2]. H Yamazaki, et al. Bufuralol hydroxylation by cytochrome P450 2D6 and 1A2 enzymes in human liver microsomes. Mol Pharmacol. 1994 Sep;46(3):568-77.

Density	1.139g/cm3
Boiling Point	433ºC at 760mmHg
Melting Point	41-49ºC
Molecular Formula	C₁₆H₂₃NO₃
Molecular Weight	277.35900
Flash Point	215.7ºC
Exact Mass	277.16800
PSA	65.63000
LogP	3.29850
Index of Refraction	1.577

Precursor 1
64100-62-5
DownStream 0