Shanghai Nianxing Industrial Co., Ltd
China
Product Name: KP372-1(PDK1/Akt/Flt Dual Inhibitor)
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: PDK1/Akt/Flt Inhibitor 1
Price: $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: PDK1/Akt/Flt Inhibitor 1
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

331253-86-2

331253-86-2 structure

331253-86-2 structure

Name: KP-23172
Chemical Name: 10H-Indeno[2,1-e]tetrazolo[1,5-b][1,2,4]triazin-10-one
CAS Number: 331253-86-2
Molecular Formula: C₁₀H₄N₆O
Molecular Weight: 224.17800
Catalog: Signaling Pathways PI3K/Akt/mTOR Akt
Create Date: 2018-06-13 21:22:32
Modify Date: 2025-08-24 21:42:48
KP-23172 is a PI3-K/Akt pathway inhibitor extracted from patent US7196083[1].

Name	10H-Indeno[2,1-e]tetrazolo[1,5-b][1,2,4]triazin-10-one
Synonyms	p-Dimethylaminophenyl-isopropyl-sulfid PDK1/Akt/Flt Dual Pathway Inhibitor Benzenamine,N,N-dimethyl-4-[(1-methylethyl)thio]

Description	KP-23172 is a PI3-K/Akt pathway inhibitor extracted from patent US7196083[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PI3K/Akt/mTOR >> PI3K Signaling Pathways >> PI3K/Akt/mTOR >> Akt
Target	PI3-K Akt
In Vitro	KP-23172 (10 µM; 60 min) significantly augments NRP-induced apoptosis [1].
References	[1]. Xi RG, et al. Roles of PI3-K/Akt pathways in nanoparticle realgar powders-induced apoptosis in U937 cells. Acta Pharmacol Sin. 2008 Mar;29(3):355-63.

Molecular Formula	C₁₀H₄N₆O
Molecular Weight	224.17800
Exact Mass	224.04500
PSA	85.93000
LogP	0.12570
Storage condition	-20℃

2165-21-1 structure

2165-21-1

485-47-2 structure

485-47-2

~%

329710-24-9 structure

329710-24-9

331253-86-2 structure

331253-86-2

Literature: Hybrigenics S.A. Patent: EP1918292 A1, 2008 ; Location in patent: Page/Page column 18-19 ; EP 1918292 A1

Precursor 2
2165-21-1 485-47-2
DownStream 0

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