331253-86-2
331253-86-2 structure
- Name: KP-23172
- Chemical Name: 10H-Indeno[2,1-e]tetrazolo[1,5-b][1,2,4]triazin-10-one
- CAS Number: 331253-86-2
- Molecular Formula: C10H4N6O
- Molecular Weight: 224.17800
- Catalog: Signaling Pathways PI3K/Akt/mTOR Akt
- Create Date: 2018-06-13 21:22:32
- Modify Date: 2024-04-02 14:48:01
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KP-23172 is a PI3-K/Akt pathway inhibitor extracted from patent US7196083[1].
| Name | 10H-Indeno[2,1-e]tetrazolo[1,5-b][1,2,4]triazin-10-one |
|---|---|
| Synonyms |
p-Dimethylaminophenyl-isopropyl-sulfid
PDK1/Akt/Flt Dual Pathway Inhibitor Benzenamine,N,N-dimethyl-4-[(1-methylethyl)thio] |
| Description | KP-23172 is a PI3-K/Akt pathway inhibitor extracted from patent US7196083[1]. |
|---|---|
| Related Catalog | |
| Target |
PI3-K Akt |
| In Vitro | KP-23172 (10 µM; 60 min) significantly augments NRP-induced apoptosis [1]. |
| References |
| Molecular Formula | C10H4N6O |
|---|---|
| Molecular Weight | 224.17800 |
| Exact Mass | 224.04500 |
| PSA | 85.93000 |
| LogP | 0.12570 |
| Storage condition | -20℃ |
|
~%
331253-86-2 |
| Literature: Hybrigenics S.A. Patent: EP1918292 A1, 2008 ; Location in patent: Page/Page column 18-19 ; EP 1918292 A1 |
