Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 3-[(1S,2S)-2-Hydroxycyclohexyl]-6-[(6-methyl-3-pyridinyl)methyl]benzo[h]quinazolin-4(3H)-one
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

1227923-29-6

1227923-29-6 structure

Name: MK-7622
Chemical Name: 3-[(1S,2S)-2-Hydroxycyclohexyl]-6-[(6-methyl-3-pyridinyl)methyl]b enzo[h]quinazolin-4(3H)-one
CAS Number: 1227923-29-6
Molecular Formula: C₂₅H₂₅N₃O₂
Molecular Weight: 399.485
Catalog: Signaling Pathways GPCR/G Protein mAChR
Create Date: 2018-06-15 18:55:09
Modify Date: 2026-07-02 13:20:56
MK-7622 is a muscarinic M1 receptor positive allosteric modulator.Target: M1 receptorMK-7622 is useful in the treatment of diseases in which the M1 receptor is involved, such as Alzheimer's disease, schizophrenia, pain or sleep disorders.

Name	3-[(1S,2S)-2-Hydroxycyclohexyl]-6-[(6-methyl-3-pyridinyl)methyl]b enzo[h]quinazolin-4(3H)-one
Synonyms	MK7622 3-[(1S,2S)-2-hydroxycyclohexyl]-6-[(6-methylpyridin-3-yl)methyl]benzo[h]quinazolin-4(3H)-one 3-[(1S,2S)-2-hydroxycyclohexyl]-6-[(6-methylpyridin-3-yl)methyl]benzo[h]quinazolin-4-one MK-7622, 10 mM in DMSO M1 rector modulator 3-[(1S,2S)-2-hydroxycyclohexyl]-6-[(6-methylpyridin-3-yl)methyl]-3H,4H-benzo[h]quinazolin-4-one 3-[(1S,2S)-2-Hydroxycyclohexyl]-6-[(6-methyl-3-pyridinyl)methyl]benzo[h]quinazolin-4(3H)-one MK7622; MK 7622; MK-7622 Benzo[h]quinazolin-4(3H)-one, 3-[(1S,2S)-2-hydroxycyclohexyl]-6-[(6-methyl-3-pyridinyl)methyl] (S)-3-(1-AMINOETHYL)BENZENAMINE 3-((1S,2S)-2-hydroxycyclohexyl)-6-((6-Methylpyridin-3-yl)Methyl)benzo[h]quinazolin-4(3H)-one 3-[(1S)-1-azanylethyl]aniline (S)-1-(3-Aminophenyl)-1-aminoethane MK-7622;MK 7622;M1 RECTOR MODULATOR MK-7622,mAChR,MK7622,inhibit,Inhibitor,Muscinic acetylcholine rector,MK M1 rector

Description	MK-7622 is a muscarinic M1 receptor positive allosteric modulator.Target: M1 receptorMK-7622 is useful in the treatment of diseases in which the M1 receptor is involved, such as Alzheimer's disease, schizophrenia, pain or sleep disorders.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> mAChR Signaling Pathways >> Neuronal Signaling >> mAChR Research Areas >> Neurological Disease
References	[1]. Kuduk Scott D, et al. Dihydrobenzoquinazolinone M1 receptor positive allosteric modulators. From PCT Int. Appl. (2012), WO 2012047702 A1 20120412. [2]. Kuduk Scott D, et al. Benzoquinazolinone derivatives as M1 receptor positive allosteric modulators and their preparation, pharmaceutical compositions and use in the treatment of diseases. From PCT Int. Appl. (2010), WO 2010059773 A1 20100527.

1227923-94-5

5158-46-3

1227923-29-6

Literature: WO2012/47702 A1, ; Page/Page column 39 ; WO 2012/047702 A1

Precursor 2
1227923-94-5 5158-46-3
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