120163-18-0

120163-18-0 structure

Name: Obtusifolin-2-O-glucoside
Chemical Name: 8-hydroxy-1-methoxy-3-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyanthracene-9,10-dione
CAS Number: 120163-18-0
Molecular Formula: C₂₂H₂₂O₁₀
Molecular Weight: 446.40400
Catalog: Signaling Pathways Metabolic Enzyme/Protease Tyrosinase
Create Date: 2016-02-25 04:14:39
Modify Date: 2024-02-08 09:06:27
Obtusifolin-2-O-glucoside (compound 7) is a Tyrosinase inhibitor (IC50=9.2 μM). Obtusifolin-2-O-glucoside can be isolated from cassia seed[1].

Name	8-hydroxy-1-methoxy-3-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyanthracene-9,10-dione
Synonyms	Obtusifolin 2-glucoside gluco-obtusifolin

Description	Obtusifolin-2-O-glucoside (compound 7) is a Tyrosinase inhibitor (IC50=9.2 μM). Obtusifolin-2-O-glucoside can be isolated from cassia seed[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Tyrosinase
Target	IC50: 9.2 μM (Tyrosinase)[1]
In Vitro	Obtusifolin-2-O-glucoside (化合物 7) (10 μM; 48 h) 抑制α-MSH处理的B16F10黑色素瘤细胞中的黑素生成[1]。
References	[1]. Lee GY, et al. Tyrosinase inhibitory components from the seeds of Cassia tora. Arch Pharm Res. 2018 May;41(5):490-496.