120163-18-0

120163-18-0 structure
120163-18-0 structure
  • Name: Obtusifolin-2-O-glucoside
  • Chemical Name: 8-hydroxy-1-methoxy-3-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyanthracene-9,10-dione
  • CAS Number: 120163-18-0
  • Molecular Formula: C22H22O10
  • Molecular Weight: 446.40400
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease Tyrosinase
  • Create Date: 2016-02-25 04:14:39
  • Modify Date: 2024-02-08 09:06:27
  • Obtusifolin-2-O-glucoside (compound 7) is a Tyrosinase inhibitor (IC50=9.2 μM). Obtusifolin-2-O-glucoside can be isolated from cassia seed[1].

Name 8-hydroxy-1-methoxy-3-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyanthracene-9,10-dione
Synonyms Obtusifolin 2-glucoside
gluco-obtusifolin
Description Obtusifolin-2-O-glucoside (compound 7) is a Tyrosinase inhibitor (IC50=9.2 μM). Obtusifolin-2-O-glucoside can be isolated from cassia seed[1].
Related Catalog
Target

IC50: 9.2 μM (Tyrosinase)[1]

In Vitro Obtusifolin-2-O-glucoside (化合物 7) (10 μM; 48 h) 抑制α-MSH处理的B16F10黑色素瘤细胞中的黑素生成[1]。
References

[1]. Lee GY, et al. Tyrosinase inhibitory components from the seeds of Cassia tora. Arch Pharm Res. 2018 May;41(5):490-496.  

Density 1.567g/cm3
Boiling Point 790.3ºC at 760 mmHg
Molecular Formula C22H22O10
Molecular Weight 446.40400
Flash Point 278.2ºC
Exact Mass 446.12100
PSA 162.98000
Vapour Pressure 2.51E-26mmHg at 25°C
Index of Refraction 1.68