956958-53-5

956958-53-5 structure

Name: XL147
Chemical Name: N-[3-(2,1,3-benzothiadiazol-5-ylamino)quinoxalin-2-yl]-4-methylbenzenesulfonamide
CAS Number: 956958-53-5
Molecular Formula: C₂₁H₁₆N₆O₂S₂
Molecular Weight: 448.52100
Catalog: Biochemical Inhibitor PI3K/Akt/mTOR inhibitor (PI3K/Akt/mTOR) PI3K inhibitor
Create Date: 2018-11-30 18:43:47
Modify Date: 2024-01-11 16:41:33
Pilaralisib analogue (XL147 analogue) is a representative and selective PI3Kα inhibitor extracted from patent WO2012006552A1, Compound 147 in Table 1.

Name	N-[3-(2,1,3-benzothiadiazol-5-ylamino)quinoxalin-2-yl]-4-methylbenzenesulfonamide
Synonyms	XL 147 XL-147 XL147 PI3K inhibitor X SAR245408

Description	Pilaralisib analogue (XL147 analogue) is a representative and selective PI3Kα inhibitor extracted from patent WO2012006552A1, Compound 147 in Table 1.
Related Catalog	Research Areas >> Cancer
Target	PI3K-alpha
References	[1]. Carlos L. Arteaga, et al. Combinations of kinase inhibitors for the treatment of cancer. WO 2012006552 A1.