1351926-90-3

1351926-90-3 structure

Name: T338C Src-IN-1
Chemical Name: N-(3-((4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)methyl)phenyl)ethenesulfonamide
CAS Number: 1351926-90-3
Molecular Formula: C₁₇H₂₀N₆O₂S
Molecular Weight: 372.44500
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK Src
Create Date: 2017-11-30 09:12:16
Modify Date: 2024-01-11 06:52:39
T338C Src-IN-1 is a potent mutant-Src T338C inhibitor; exhibited the most potent inhibition of T338C(IC50=111 nM) relative to WT c-Src (10-fold increase).

Name	N-(3-((4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)methyl)phenyl)ethenesulfonamide
Synonyms	T338C Src-IN-1

Description	T338C Src-IN-1 is a potent mutant-Src T338C inhibitor; exhibited the most potent inhibition of T338C(IC50=111 nM) relative to WT c-Src (10-fold increase).
Related Catalog	Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Src Research Areas >> Cancer
References	[1]. Garske AL, et al. Chemical genetic strategy for targeting protein kinases based on covalent complementarity. Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15046-52.