T338C Src-IN-1

Modify Date: 2024-01-11 06:52:39

T338C Src-IN-1 Structure
T338C Src-IN-1 structure
Common Name T338C Src-IN-1
CAS Number 1351926-90-3 Molecular Weight 372.44500
Density N/A Boiling Point N/A
Molecular Formula C17H20N6O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of T338C Src-IN-1


T338C Src-IN-1 is a potent mutant-Src T338C inhibitor; exhibited the most potent inhibition of T338C(IC50=111 nM) relative to WT c-Src (10-fold increase).

 Names

Name N-(3-((4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)methyl)phenyl)ethenesulfonamide
Synonym More Synonyms

 T338C Src-IN-1 Biological Activity

Description T338C Src-IN-1 is a potent mutant-Src T338C inhibitor; exhibited the most potent inhibition of T338C(IC50=111 nM) relative to WT c-Src (10-fold increase).
Related Catalog
References

[1]. Garske AL, et al. Chemical genetic strategy for targeting protein kinases based on covalent complementarity. Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15046-52.

 Chemical & Physical Properties

Molecular Formula C17H20N6O2S
Molecular Weight 372.44500
Exact Mass 372.13700
PSA 124.17000
LogP 4.20040
Storage condition 2-8℃

 Synonyms

T338C Src-IN-1
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