| Name | 5,6-Dimethoxy-2H-furo[2,3-h]chromen-2-one |
|---|---|
| Synonyms |
5,6-Dimethoxy-2H-furo[2,3-h]chromen-2-one
2H-Furo[2,3-h]-1-benzopyran-2-one, 5,6-dimethoxy- 5,6-dimethoxyfuro[2,3-h]chromen-2-one 4-Hydroxy-6,7-dimethoxy-5-benzofuranacrylic Acid d-Lactone 5,6-Dimethoxy-2H-furo[2,3-h]-1-benzopyran-2-one Pimpinellin |
| Description | Pimpinellin is a constituent of Cyrtomium fortumei (J.). Pimpinellin inhibits the growth of tumor cells via the induction of tumor cell apoptosis[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Pimpinellin has potent cytotoxic activities against the three tumor cells MGC-803, PC3, and A375, with the IC50 values of 14.4±0.3 μM, 20.4±0.5 μM, and 29.2±0.6 μM, respectively. Pimpinellin inhibits the growth of MGC-803 cells via the induction of tumor cell apoptosis, with apoptosis ratio of 27.44% after 72 h of treatment at 20 μM[1]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 441.0±45.0 °C at 760 mmHg |
| Melting Point | 119° |
| Molecular Formula | C13H10O5 |
| Molecular Weight | 246.215 |
| Flash Point | 220.5±28.7 °C |
| Exact Mass | 246.052826 |
| PSA | 61.81000 |
| LogP | 2.06 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.612 |
| Storage condition | 2-8C |
| HS Code | 2932999099 |
|---|
|
~81%
131-12-4 |
| Literature: Reed, Michael W.; Moore, Harold W. Journal of Organic Chemistry, 1988 , vol. 53, # 8 p. 4166 - 4171 |
|
~16%
131-12-4 |
| Literature: Bioorganic and Medicinal Chemistry, , vol. 7, # 9 p. 1933 - 1940 |
|
~%
131-12-4 |
| Literature: Journal of Organic Chemistry, , vol. 53, # 8 p. 4166 - 4171 |
|
~%
131-12-4 |
| Literature: Journal of Organic Chemistry, , vol. 53, # 8 p. 4166 - 4171 |
|
~%
131-12-4 |
| Literature: Journal of Organic Chemistry, , vol. 53, # 8 p. 4166 - 4171 |
|
~%
131-12-4 |
| Literature: Journal of Organic Chemistry, , vol. 53, # 8 p. 4166 - 4171 |
|
~%
131-12-4 |
| Literature: Bioorganic and Medicinal Chemistry, , vol. 7, # 9 p. 1933 - 1940 |
| HS Code | 2932999099 |
|---|---|
| Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |