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  • Product Name: Pimpinellin
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131-12-4

131-12-4 structure
131-12-4 structure
  • Name: Pimpinellin
  • Chemical Name: 5,6-Dimethoxy-2H-furo[2,3-h]chromen-2-one
  • CAS Number: 131-12-4
  • Molecular Formula: C13H10O5
  • Molecular Weight: 246.215
  • Catalog: Biochemical Amino acids and their derivatives Leucine derivative
  • Create Date: 2018-02-26 08:00:00
  • Modify Date: 2024-01-04 07:05:59
  • Pimpinellin is a constituent of Cyrtomium fortumei (J.). Pimpinellin inhibits the growth of tumor cells via the induction of tumor cell apoptosis[1].

Name 5,6-Dimethoxy-2H-furo[2,3-h]chromen-2-one
Synonyms 5,6-Dimethoxy-2H-furo[2,3-h]chromen-2-one
2H-Furo[2,3-h]-1-benzopyran-2-one, 5,6-dimethoxy-
5,6-dimethoxyfuro[2,3-h]chromen-2-one
4-Hydroxy-6,7-dimethoxy-5-benzofuranacrylic Acid d-Lactone
5,6-Dimethoxy-2H-furo[2,3-h]-1-benzopyran-2-one
Pimpinellin
Description Pimpinellin is a constituent of Cyrtomium fortumei (J.). Pimpinellin inhibits the growth of tumor cells via the induction of tumor cell apoptosis[1].
Related Catalog
In Vitro Pimpinellin has potent cytotoxic activities against the three tumor cells MGC-803, PC3, and A375, with the IC50 values of 14.4±0.3 μM, 20.4±0.5 μM, and 29.2±0.6 μM, respectively. Pimpinellin inhibits the growth of MGC-803 cells via the induction of tumor cell apoptosis, with apoptosis ratio of 27.44% after 72 h of treatment at 20 μM[1].
References

[1]. Yang S, et al. Discovery and antitumor activities of constituents from Cyrtomium fortumei (J.) Smith rhizomes. Chem Cent J. 2013 Feb 4;7(1):24.

Density 1.4±0.1 g/cm3
Boiling Point 441.0±45.0 °C at 760 mmHg
Melting Point 119°
Molecular Formula C13H10O5
Molecular Weight 246.215
Flash Point 220.5±28.7 °C
Exact Mass 246.052826
PSA 61.81000
LogP 2.06
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.612
Storage condition 2-8C
HS Code 2932999099

~81%

131-12-4 structure

131-12-4

Literature: Reed, Michael W.; Moore, Harold W. Journal of Organic Chemistry, 1988 , vol. 53, # 8 p. 4166 - 4171

~16%

131-12-4 structure

131-12-4

Literature: Bioorganic and Medicinal Chemistry, , vol. 7, # 9 p. 1933 - 1940

~%

131-12-4 structure

131-12-4

Literature: Journal of Organic Chemistry, , vol. 53, # 8 p. 4166 - 4171

~%

131-12-4 structure

131-12-4

Literature: Journal of Organic Chemistry, , vol. 53, # 8 p. 4166 - 4171

~%

131-12-4 structure

131-12-4

Literature: Journal of Organic Chemistry, , vol. 53, # 8 p. 4166 - 4171

~%

131-12-4 structure

131-12-4

Literature: Journal of Organic Chemistry, , vol. 53, # 8 p. 4166 - 4171

~%

131-12-4 structure

131-12-4

Literature: Bioorganic and Medicinal Chemistry, , vol. 7, # 9 p. 1933 - 1940
HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%