14985-44-5

14985-44-5 structure

Name: 8-Bromo-2'-deoxyadenosine
Chemical Name: 8-Bromo-2'-deoxyadenosine
CAS Number: 14985-44-5
Molecular Formula: C₁₀H₁₂BrN₅O₃
Molecular Weight: 330.14
Catalog: Biochemical Nucleoside drugs Deoxynucleotides and their analogues
Create Date: 2018-06-09 09:23:09
Modify Date: 2026-07-09 13:20:02
8-Bromo-2'-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	8-Bromo-2'-deoxyadenosine
Synonyms	8-bromo-deoxyadenosine (2R,3S,5R)-5-(6-Amino-8-broMo-9H-purin-9-yl)-2-(hydroxyMethyl)tetrahydrofuran-3-ol 8-Br-2'-dA 8-BROMO-2''-DEOXYADENOSINE, HPLC PURIFIED, UV CHROMATOAM 8-BROMO-2'-DEOXYADENOSINE //BP 8-Bromo-2’-deoxyadenosine (2R,3S,5R)-5-(6-Amino-8-bromo-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol (2R,3S,5R)-5-(6-amino-8-bromo-9H-purin-9-yl)-2-(hydroxymethyl)oxolan-3-ol 5-(6-Amino-8-bromo-9H-purin-9-yl) 8-BROMO-2'-DEOXY-D-ADENOSINE Adenosine,8-bromo-2'-deoxy 5-(6-AMINO-8-BROMO-PURIN-9-YL)-2-HYDROXYMETHYL-TETRAHYDRO-FURAN-3-OL 8-Br-dA 8-bromo-2'-deoxydenosine 8-bromo-2'-deoxy-adenosine 8-Bromodeoxyadenosine (2R,3S,5R)-5-(6-amino-8-bromopurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol 8-Bromo-9-(2'-deoxyribofuranosyl)adenine

Description	8-Bromo-2'-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

958-09-8

~88%

14985-44-5

Literature: Helvetica Chimica Acta, , vol. 71, p. 1566 - 1572