Name | 8-Bromo-2'-deoxyadenosine |
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Synonyms |
8-Br-dA
(2R,3S,5R)-5-(6-Amino-8-bromo-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol 8-Bromo-9-(2'-deoxyribofuranosyl)adenine 8-bromo-2'-deoxy-adenosine 8-bromo-deoxyadenosine 8-bromo-2'-deoxydenosine 8-BROMO-2'-DEOXY-D-ADENOSINE |
Description | 8-Bromo-2'-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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Related Catalog | |
References |
Density | 2.3g/cm3 |
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Boiling Point | 671ºC at 760mmHg |
Molecular Formula | C10H12BrN5O3 |
Molecular Weight | 330.14 |
Flash Point | 359.6ºC |
Exact Mass | 329.01200 |
PSA | 119.31000 |
LogP | 0.39290 |
Appearance | Powder | White to Yellow |
Vapour Pressure | 6.41E-19mmHg at 25°C |
Index of Refraction | 1.898 |
Water Solubility | Soluble in DMSO or DMF |
~88% 14985-44-5 |
Literature: Helvetica Chimica Acta, , vol. 71, p. 1566 - 1572 |