Shanghai Nianxing Industrial Co., Ltd
China
Product Name: hydroxyprogesterone caproate
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

DC Chemicals Limited
China
Product Name: Hydroxyprogesterone caproate
Price: $100.0/100mg $200.0/250mg $400.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

ShangHai DC Chemicals Co.,Ltd
China
Product Name: Hydroxyprogesterone caproate
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Lai

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Hydroxyprogesterone caproate
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Henan Tianfu Chemical Co., Ltd.
China
Product Name: HYDROXIPROGESTRONE CAPROATE - 50KG
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

630-56-8

630-56-8 structure

Name: hydroxyprogesterone caproate
Chemical Name: 17α-Caproyloxyprogesterone
CAS Number: 630-56-8
Molecular Formula: C₂₇H₄₀O₄
Molecular Weight: 428.604
Catalog: API Hormone and endocrine-regulating drugs Birth control pills
Create Date: 2018-05-15 08:00:00
Modify Date: 2024-01-03 03:52:55
Hydroxyprogesterone caproate is a synthetic, steroidal progestin; an ester derivative of 17α-hydroxyprogesterone formed from caproic acid.

Name	17α-Caproyloxyprogesterone
Synonyms	Progesterone, 17-hydroxy-, hexanoate [(8R,9S,10R,13S,14S,17R)-17-acetyl-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] hexanoate 17-Hydroxypregn-4-ene-3,20-dione hexanoate 3,20-Dioxopregn-4-en-1-yl hexanoate hydroxyprogesterone caproate EINECS 211-138-8 17α-Caproyloxypregn-4-ene-3,20-dione 17-((1-Oxohexyl)oxy)pregn-4-ene-3,20-dione Proluton depot 17-α-Hydroxyprogesterone hexanoate 17α-Hydroxyprogesterone hexanoate Delalutin 3,20-Dioxopregn-4-en-17-ylhexanoat Gesterol LA 250 Pregn-4-ene-3,20-dione, 17-((1-oxohexyl)oxy)- Pharlon Hexanoic acid, 3,20-dioxopregn-4-en-1-yl ester Pregn-4-ene-3,20-dione, 17-hydroxy-, hexanoate (8R,9S,10R,13S,14S,17R)-17-acetyl-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl hexanoate 17-α-Hexanoyloxypregn-4-ene-3,20-dione 17-α-hydroxy-progesterone caproate MFCD00072134 Pregn-4-ene-3,20-dione, 17-[(1-oxohexyl)oxy]- 17-α-Hydroxyprogesterone caproate Teralutil 17a-Hydroxyprogesterone caproate Hexanoic acid, 3,20-dioxopregn-4-en-17-yl ester 17a-Hydroxyprogesterone Hexanoate 17α-Hydroxyprogesterone caproate Proge 3,20-Dioxopregn-4-en-17-yl hexanoate 17-[(1-Oxohexyl)oxy]pregn-4-ene-3,20-dione

Description	Hydroxyprogesterone caproate is a synthetic, steroidal progestin; an ester derivative of 17α-hydroxyprogesterone formed from caproic acid.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Others
References	[1]. Armstrong J. Unintended consequences--the cost of preventing preterm births after FDA approval of a branded version of 17OHP. N Engl J Med. 2011 May 5;364(18):1689-91. [2]. Hauth JC, et al. The effect of 17 alpha-hydroxyprogesterone caproate on pregnancy outcome in an active-duty military population. Am J Obstet Gynecol. 1983 May 15;146(2):187-90.

Density	1.1±0.1 g/cm3
Boiling Point	540.0±50.0 °C at 760 mmHg
Melting Point	119°C
Molecular Formula	C₂₇H₄₀O₄
Molecular Weight	428.604
Flash Point	229.2±30.2 °C
Exact Mass	428.292664
PSA	60.44000
LogP	5.53
Vapour Pressure	0.0±1.4 mmHg at 25°C
Index of Refraction	1.532
Storage condition	2~8℃

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TU5085000

CHEMICAL NAME :: Pregn-4-ene-3,20-dione, 17-hydroxy-, hexanoate

CAS REGISTRY NUMBER :: 630-56-8

LAST UPDATED :: 199706

DATA ITEMS CITED :: 11

MOLECULAR FORMULA :: C27-H40-O4

MOLECULAR WEIGHT :: 428.67

WISWESSER LINE NOTATION :: L E5 B666 OV MUTJ A1 E1 FV1 FOV5

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Unreported

DOSE :: 12 mg/kg

SEX/DURATION :: female 6-20 week(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - behavioral

REFERENCE :: SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year: 211,1171,1981

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intramuscular

DOSE :: 700 mg/kg

SEX/DURATION :: female 18-24 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Effects on Embryo or Fetus - fetal death

REFERENCE :: TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 31,48A,1985

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Implant

DOSE :: 30 mg/kg

SEX/DURATION :: male 20 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females)

REFERENCE :: IJEBA6 Indian Journal of Experimental Biology. (Publications & Information Directorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- Volume(issue)/page/year: 18,1225,1980

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Implant

DOSE :: 61953 ug/kg

SEX/DURATION :: male 26 week(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)

REFERENCE :: IJEBA6 Indian Journal of Experimental Biology. (Publications & Information Directorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- Volume(issue)/page/year: 18,1225,1980

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Implant

DOSE :: 45157 ug/kg

SEX/DURATION :: male 17 week(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - testes, epididymis, sperm duct

REFERENCE :: IJEBA6 Indian Journal of Experimental Biology. (Publications & Information Directorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- Volume(issue)/page/year: 18,1225,1980

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 4160 mg/kg

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

REFERENCE :: TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 28,201,1983

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Implant

DOSE :: 650 mg/kg

SEX/DURATION :: female 6-18 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - other effects to embryo

REFERENCE :: TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 35,28A,1987

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intramuscular

DOSE :: 180 mg/kg

SEX/DURATION :: female 3-21 week(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetal death

REFERENCE :: TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 35,129,1987 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 21,399,1979 TOXICOLOGY REVIEW TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 21,225,1980 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X6069 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 628 (estimated) No. of Female Employees: 314 (estimated)

Symbol	GHS08
Signal Word	Danger
Hazard Statements	H360
Precautionary Statements	P201-P280-P308 + P313
Hazard Codes	T: Toxic;
Risk Phrases	R61
Safety Phrases	S53-S22-S36/37/39-S45
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	TU5085000

Precursor 0
DownStream 1
1096-38-4

630-56-8	302-23-8
61358-54-1	6290-37-5
101330-34-1	123-68-2
94617-29-5	36761-57-6
1035560-36-1	13170-69-9
1158522-08-7	940364-43-2
134104-43-1	131615-57-1
2229005-74-5	1222196-20-4
6906-52-1	787524-72-5
930439-75-1	1018584-77-4