16524-22-4

16524-22-4 structure

Name: 3-MFA
Chemical Name: 2-(3-methylanilino)benzoic acid
CAS Number: 16524-22-4
Molecular Formula: C₁₄H₁₃NO₂
Molecular Weight: 227.25900
Create Date: 2018-12-21 11:35:42
Modify Date: 2024-01-10 11:37:47

Name	2-(3-methylanilino)benzoic acid
Synonyms	N-m-Tolylanthranilic acid 2-(3-Methylphenyl)aminobenzoic acid N-m-Tolyl-anthranilsaeure 2-m-Toluidino-benzoesaeure 2-[(3-Methylphenyl)Amino]-Benzoic Acid

Density	1.233g/cm3
Boiling Point	391.6ºC at 760mmHg
Melting Point	136-137 °C
Molecular Formula	C₁₄H₁₃NO₂
Molecular Weight	227.25900
Flash Point	190.6ºC
Exact Mass	227.09500
PSA	49.33000
LogP	3.50980
Vapour Pressure	7.81E-07mmHg at 25°C
Index of Refraction	1.652

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CB4170000

CHEMICAL NAME :: Anthranilic acid, N-(m-tolyl)-

CAS REGISTRY NUMBER :: 16524-22-4

BEILSTEIN REFERENCE NO. :: 2214283

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C14-H13-N-O2

MOLECULAR WEIGHT :: 227.28

WISWESSER LINE NOTATION :: QVR BMR C1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 94 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 89,1392,1969

Symbol	GHS07, GHS09
Signal Word	Warning
Hazard Statements	H302-H315-H319-H335-H411
Precautionary Statements	P261-P273-P305 + P351 + P338
Hazard Codes	Xi
RIDADR	UN 3077 9 / PGIII
HS Code	2922499990

108-44-1

118-91-2

~77%

16524-22-4

Literature: Mei, Xuefeng; August, Adam T.; Wolf, Christian Journal of Organic Chemistry, 2006 , vol. 71, # 1 p. 142 - 149

23868-14-6

~74%

16524-22-4

Literature: Adeniji, Adegoke O.; Twenter, Barry M.; Byrns, Michael C.; Jin, Yi; Chen, Mo; Winkler, Jeffrey D.; Penning, Trevor M. Journal of Medicinal Chemistry, 2012 , vol. 55, # 5 p. 2311 - 2323

1488-42-2

108-44-1

~47%

16524-22-4

Literature: Chalmers; Scholz; Topliss; Kolliniatis; Munro; Craik; Iskander; Stockigt Journal of Medicinal Chemistry, 1993 , vol. 36, # 9 p. 1272 - 1277

108-44-1

~78%

16524-22-4

Literature: Di Fusco, Massimo; Quintavalla, Arianna; Trombini, Claudio; Lombardo, Marco; Roda, Aldo; Guardigli, Massimo; Mirasoli, Mara Journal of Organic Chemistry, 2013 , vol. 78, # 22 p. 11238 - 11246

16497-87-3

108-44-1

16524-22-4

Literature: Kaltenbronn; Scherrer; Short; Jones; Beatty; Saka; Winder; Wax; Williamson Arzneimittel-Forschung/Drug Research, 1983 , vol. 33, # 4 A p. 621 - 627

17763-70-1

108-44-1

16524-22-4

Literature: Adeniji, Adegoke O.; Twenter, Barry M.; Byrns, Michael C.; Jin, Yi; Chen, Mo; Winkler, Jeffrey D.; Penning, Trevor M. Journal of Medicinal Chemistry, 2012 , vol. 55, # 5 p. 2311 - 2323

Precursor 5
108-44-1 118-91-2 23868-14-6 1488-42-2
17763-70-1
DownStream 4
1205-64-7 16492-10-7 65753-71-1 57165-19-2

HS Code	2922499990
Summary	HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

16524-22-4	141080-31-1
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141079-06-3	141079-01-8
141078-99-1	141078-96-8
141078-91-3	141075-92-5