Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1-(2-Pyridinyl)-4-(4-((7-(trifluoromethyl)-4-quinolinyl)amino)benzoyl) piperazine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

72141-45-8

72141-45-8 structure

72141-45-8 structure

Name: 1-(2-Pyridinyl)-4-(4-((7-(trifluoromethyl)-4-quinolinyl)amino)benzoyl) piperazine
Chemical Name: (4-pyridin-2-ylpiperazin-1-yl)-[4-[[7-(trifluoromethyl)quinolin-4-yl]amino]phenyl]methanone
CAS Number: 72141-45-8
Molecular Formula: C₂₆H₂₂F₃N₅O
Molecular Weight: 477.48100
Create Date: 2017-12-27 10:49:49
Modify Date: 2024-01-16 09:42:52

Name	(4-pyridin-2-ylpiperazin-1-yl)-[4-[[7-(trifluoromethyl)quinolin-4-yl]amino]phenyl]methanone

Density	1.364g/cm3
Boiling Point	652.7ºC at 760 mmHg
Molecular Formula	C₂₆H₂₂F₃N₅O
Molecular Weight	477.48100
Flash Point	348.5ºC
Exact Mass	477.17800
PSA	61.36000
LogP	5.43050
Index of Refraction	1.652

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TM2765200

CHEMICAL NAME :: Piperazine, 1-(2-pyridinyl)-4-(4-((7-(trifluoromethyl)-4-quinolin yl)amino)benzoyl)-

CAS REGISTRY NUMBER :: 72141-45-8

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C26-H22-F3-N5-O

MOLECULAR WEIGHT :: 477.53

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1395 mg/kg

TOXIC EFFECTS :: Vascular - BP lowering not characterized in autonomic section

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 29,133,1986

109-09-1 structure

109-09-1

72141-43-6 structure

72141-43-6

~73%

72141-45-8 structure

72141-45-8

Literature: McCall, John M.; TenBrink, R. E.; Kamdar, Bharat V.; Skaletzky, Louis L.; Perricone, Salvatore C.; et al. Journal of Medicinal Chemistry, 1986 , vol. 29, # 1 p. 133 - 137

Precursor 2
109-09-1 72141-43-6
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