964-21-6

964-21-6 structure

Name: 6-O-Methyldeoxyguanosine
Chemical Name: O6-methyl-2'-deoxyguanosine
CAS Number: 964-21-6
Molecular Formula: C₁₁H₁₅N₅O₄
Molecular Weight: 281.27
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2017-05-19 05:57:29
Modify Date: 2024-01-14 11:39:59
O6-Methyldeoxy guanosine; DNA adduct is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	O6-methyl-2'-deoxyguanosine
Synonyms	O6-methyl-2'-deoxy-guanosine 2-Amino-6-methoxy-2'-deoxy-6-deaminoadenosine 6-O-METHYL-2'-DEOXYGUANOSINE O(6)-methyl-2'-deoxyguanosine O6-METHYL-2'-DEOXYGUANOSINE O6-methyldeoxyguanosine

Description	O6-Methyldeoxy guanosine; DNA adduct is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.