6-O-Methyldeoxyguanosine

Modify Date: 2024-01-14 11:39:59

6-O-Methyldeoxyguanosine Structure
6-O-Methyldeoxyguanosine structure
Common Name 6-O-Methyldeoxyguanosine
CAS Number 964-21-6 Molecular Weight 281.27
Density 1.84 g/cm3 Boiling Point 674.7ºC at 760 mmHg
Molecular Formula C11H15N5O4 Melting Point N/A
MSDS N/A Flash Point 361.9ºC

 Use of 6-O-Methyldeoxyguanosine


O6-Methyldeoxy guanosine; DNA adduct is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name O6-methyl-2'-deoxyguanosine
Synonym More Synonyms

 6-O-Methyldeoxyguanosine Biological Activity

Description O6-Methyldeoxy guanosine; DNA adduct is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.84 g/cm3
Boiling Point 674.7ºC at 760 mmHg
Molecular Formula C11H15N5O4
Molecular Weight 281.27
Flash Point 361.9ºC
Exact Mass 281.11200
PSA 128.54000
Index of Refraction 1.794
Storage condition 2-8°C

 Synthetic Route

 Synonyms

O6-methyl-2'-deoxy-guanosine
2-Amino-6-methoxy-2'-deoxy-6-deaminoadenosine
6-O-METHYL-2'-DEOXYGUANOSINE
O(6)-methyl-2'-deoxyguanosine
O6-METHYL-2'-DEOXYGUANOSINE
O6-methyldeoxyguanosine
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