Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2-(5-amino-2,4,9-triazabicyclo[4.3.0]nona-1,3,5,7-tetraen-9-yl)-5-(hydroxymethyl)oxolan-3-ol
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Purity: 98.0%
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40725-89-1

40725-89-1 structure

Name: 2-(5-amino-2,4,9-triazabicyclo[4.3.0]nona-1,3,5,7-tetraen-9-yl)-5-(hydroxymethyl)oxolan-3-ol
Chemical Name: 2-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)oxolan-3-ol
CAS Number: 40725-89-1
Molecular Formula: C₁₁H₁₄N₄O₃
Molecular Weight: 250.25
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2016-07-06 08:54:11
Modify Date: 2025-08-25 11:38:48
7-(3-Deoxy-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	2-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)oxolan-3-ol
Synonyms	Tubercidin-5'-phosphat tubercidin-5-monophosphate 3'-deoxytubercidin TUBERCIDIN-5'-O-MONOPHOSPHATE SODIUM SALT 7-deaza-[5']adenylic acid 7-CH-5'-AMP SODIUM SALT 7-DEAZAADENOSINE-5'-O-MONOPHOSPHATE SODIUM SALT 5'-deoxy-5'-(methylthio)tubercidin tubercidin 5'-phosphate

Description	7-(3-Deoxy-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

CHEMICAL NAME :: 7H-Pyrrolo(2,3-d)pyrimidin-4-amine, 7-(3-deoxy-beta-D-erythro-pentofuranosyl)-

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 30,481,1987

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40627-30-3