311795-38-7

311795-38-7 structure

Name: Glutaminase C-IN-1
Chemical Name: 5-[3-bromo-4-(dimethylamino)phenyl]-2,2-dimethyl-1,3,5,6-tetrahydrobenzo[a]phenanthridin-4-one
CAS Number: 311795-38-7
Molecular Formula: C₂₇H₂₇BrN₂O
Molecular Weight: 475.42000
Catalog: Research Areas Cancer
Create Date: 2018-12-26 22:41:47
Modify Date: 2024-01-09 18:36:07
Glutaminase C-IN-1 (968) is an allosteric inhibitor of Glutaminase C that inhibits cancer cell growth without affecting their normal cellular counterparts.

Name	5-[3-bromo-4-(dimethylamino)phenyl]-2,2-dimethyl-1,3,5,6-tetrahydrobenzo[a]phenanthridin-4-one
Synonyms	QC-219 5-[3-bromo-4-(dimethylamino)phenyl]-2,2-dimethyl-2,3,5,6-tetrahydrobenzo[a]phenanthridin-4(1H)-one Glutaminase C-IN-1

Description	Glutaminase C-IN-1 (968) is an allosteric inhibitor of Glutaminase C that inhibits cancer cell growth without affecting their normal cellular counterparts.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Cancer
References	[1]. Stalnecker CA, et al. Mechanism by which a recently discovered allosteric inhibitor blocks glutamine metabolism in transformed cells. Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):394-9.

Hazard Statements	H413
RIDADR	NONH for all modes of transport