Name | guanethidine monosulfate |
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Synonyms |
1-[2-(Azocan-1-yl)ethyl]guanidine sulfate (1:1)
EINECS 211-442-0 Iporal Guanethidine bisulfate 1-[2-(1-Azocanyl)ethyl]guanidine sulfate Guanidine, N-[2-(hexahydro-1(2H)-azocinyl)ethyl]-, sulfate (1:1) 2-[2-(azocan-1-yl)ethyl]guanidine,sulfuric acid Sanotensin MFCD00035403 1-[2-(1-Azocanyl)ethyl]guanidine sulfate (1:1) 1-[2-(Azocan-1-yl)ethyl]guanidine sulfate Guanethidine Sulfate Ismelin sulfate UNII-5UBY8Y002G Guanetidin sulfate Guanethidine monosulfate 1-[2-(Azocan-1-yl)ethyl]guanidinsulfat N-(2-Guanidino ethyl)heptamethylenimine sulfate 1-(2-azocan-1-ylethyl)guanidine sulfate Ismelin guanethidine sulphate |
Description | Guanethidine is an antihypertensive drug that reduces the release of catecholamines, such as norepinephrine.IC50 value:Target: Guanethidine is transported across the sympathetic nerve membrane by the same mechanism that transports norepinephrine itself (NET, uptake 1), and uptake is essential for the drug's action. Once guanethidine has entered the nerve, it is concentrated in transmitter vesicles, where it replaces norepinephrine.It may also inhibit the release of granules by decreasing norepinephrine. |
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Related Catalog | |
References |
Boiling Point | 345.6ºC at 760 mmHg |
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Molecular Formula | C10H24N4O4S |
Molecular Weight | 296.387 |
Flash Point | 162.8ºC |
Exact Mass | 296.151825 |
PSA | 148.12000 |
LogP | 2.29240 |
Storage condition | -20°C |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
|
Symbol |
![]() GHS07 |
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Signal Word | Warning |
Hazard Statements | H302 |
Precautionary Statements | P301 + P312 + P330 |
Hazard Codes | Xn: Harmful; |
Risk Phrases | R22 |
Safety Phrases | S25-S36 |
RIDADR | NONH for all modes of transport |
RTECS | MF3150000 |
HS Code | 2933990090 |
HS Code | 2933990090 |
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Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |