Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 3-Pyridinemethanol,5-hydroxy-4-(methoxymethyl)-6-methyl-, hydrochloride (1:1)
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

3131-27-9

3131-27-9 structure

Name: 3-Pyridinemethanol,5-hydroxy-4-(methoxymethyl)-6-methyl-, hydrochloride (1:1)
Chemical Name: 5-(hydroxymethyl)-4-(methoxymethyl)-2-methylpyridin-3-ol,hydrochloride
CAS Number: 3131-27-9
Molecular Formula: C₉H₁₄ClNO₃
Molecular Weight: 219.66500
Create Date: 2017-08-15 04:09:33
Modify Date: 2024-01-30 19:08:33

Name	5-(hydroxymethyl)-4-(methoxymethyl)-2-methylpyridin-3-ol,hydrochloride
Synonyms	4-Methoxymethylpyridoxol hydrochloride 2-methyl-3-hydroxy-4-methoxymethyl-5-hydroxymethylpyridine hydrochloride 5-hydroxy-4-(methoxymethyl)-6-methyl-3-pyridinemethanol,hydrochloride 4'-O-methylpyridoxine hydrochloride 5-Hydroxymethyl-4-methoxymethyl-2-methyl-pyridin-3-ol,Hydrochlorid 4-Methoxymethyl-5-hydroxy-6-methyl-3-pyridinemethanol hydrochloride 3-Pyridinemethanol,5-hydroxy-4-(methoxymethyl)-6-methyl-,hydrochloride 3-Hydroxy-5-hydroxymethyl-4-methoxymethyl-2-methylpyridine hydrochloride ginkgotoxin hydrochloride 4-Methoxymethylpyridoxine hydrochloride 5-hydroxymethyl-4-methoxymethyl-2-methyl-pyridin-3-ol,hydrochloride

Density	1.218g/cm3
Boiling Point	404.2ºC at 760 mmHg
Molecular Formula	C₉H₁₄ClNO₃
Molecular Weight	219.66500
Flash Point	198.3ºC
Exact Mass	219.06600
PSA	62.58000
LogP	1.53630
Index of Refraction	1.562

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UT5010000

CHEMICAL NAME :: 3-Pyridinemethanol, 5-hydroxy-4-(methoxymethyl)-6-methyl-, hydrochloride

CAS REGISTRY NUMBER :: 3131-27-9

LAST UPDATED :: 197906

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C9-H13-N-O3.Cl-H

MOLECULAR WEIGHT :: 219.69

WISWESSER LINE NOTATION :: T6NJ B1 CQ D1O1 E1Q &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2150 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - excitement

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 11,922,1961

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 705 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - excitement

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 11,922,1961

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 420 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - excitement

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 11,922,1961

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 75 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 11,922,1961

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 21 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 11,922,1961

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 22 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 11,922,1961

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 8 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Gastrointestinal - changes in structure or function of salivary glands Gastrointestinal - hypermotility, diarrhea

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 11,922,1961

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Bird - pigeon

DOSE/DURATION :: 5 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Behavioral - convulsions or effect on seizure threshold

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 11,922,1961

HS Code	2933399090

124-41-4

58-56-0

3131-27-9

Literature: Harris et al. Journal of the American Chemical Society, 1940 , vol. 62, p. 3198,3202

5429-57-2

3131-27-9

Literature: Merck,E. Patent: DE707266 , 1939 ; DRP/DRBP Org.Chem.

5429-57-2

10597-41-8

3131-27-9

78313-60-7

Detail

Literature: Efremenko, A. A.; Balyakina, M. V.; Gunar, V. I. Pharmaceutical Chemistry Journal, 1981 , vol. 15, # 2 p. 120 - 125 Khimiko-Farmatsevticheskii Zhurnal, 1981 , vol. 15, # 2 p. 69 - 74

Precursor 3
124-41-4 58-56-0 5429-57-2
DownStream 1
78313-59-4

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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