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192-97-2

192-97-2 structure
192-97-2 structure
  • Name: Benzo[e]pyrene
  • Chemical Name: benzo[e]pyrene
  • CAS Number: 192-97-2
  • Molecular Formula: C20H12
  • Molecular Weight: 252.309
  • Catalog: analytical chemistry Standard Cosmetic standard
  • Create Date: 2018-07-23 19:43:06
  • Modify Date: 2024-01-04 00:34:37
  • Benzo[e]pyrene occurs in fossil fuels and is a highly toxic member of a family of compounds called polyaromatic hydrocarbons (PAHs)[1].
Name benzo[e]pyrene
Synonyms 4,5-Benzopyrene
1,2-Benzpyrene,4,5-Benzpyrene
EINECS 205-892-7
Benzo[l]pyrene
MFCD00003605
9,10-Benzpyrene
Benzo(a)pyrene
benzo<e>pyrene
Benzo(l)pyrene
Benzo(e)pyrene
Benzo[e]pyrene
B(e)P
4,5-BENZPYRENE
benz[e]pyrene
1,2-Benzopyrene
1,2-Benzpyrene
Description Benzo[e]pyrene occurs in fossil fuels and is a highly toxic member of a family of compounds called polyaromatic hydrocarbons (PAHs)[1].
Related Catalog
References

[1]. Schwarz FP, et al Fluorescence measurements of benzene, naphthalene, anthracene, pyrene, fluoranthene, and benzo(e)pyrene in water. Anal Chem. 1976 Mar;48(3):524-8  

Density 1.3±0.1 g/cm3
Boiling Point 467.5±12.0 °C at 760 mmHg
Melting Point 177-180ºC(lit.)
Molecular Formula C20H12
Molecular Weight 252.309
Flash Point 228.6±13.7 °C
Exact Mass 252.093903
LogP 6.40
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.887

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DJ4200000
CHEMICAL NAME :
Benzo(e)pyrene
CAS REGISTRY NUMBER :
192-97-2
BEILSTEIN REFERENCE NO. :
1911334
LAST UPDATED :
199710
DATA ITEMS CITED :
40
MOLECULAR FORMULA :
C20-H12
MOLECULAR WEIGHT :
252.32
WISWESSER LINE NOTATION :
L D6666 B6 2AB TJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
360 mg/kg/43W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
240 mg/kg/30W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
160 mg/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - facilitates action of known carcinogen
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
140 mg/kg/37W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - facilitates action of known carcinogen
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
516 mg/kg/43W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
300 mg/kg
SEX/DURATION :
female 8 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - musculoskeletal system
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
150 mg/kg
SEX/DURATION :
female 8 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
TYPE OF TEST :
Micronucleus test
TYPE OF TEST :
DNA adduct
TYPE OF TEST :
Sister chromatid exchange

MUTATION DATA

TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Rodent - hamster Ovary
DOSE/DURATION :
1 umol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 53,284,1978 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 3,137,1973 IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 32,225,1983 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 32,225,1983 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987
Symbol GHS08 GHS09
GHS08, GHS09
Signal Word Danger
Hazard Statements H350-H410
Precautionary Statements P201-P273-P308 + P313-P501
Personal Protective Equipment Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes T,N,Xn,F
Risk Phrases 45-50/53-67-65-38-11
Safety Phrases S45;S53;S60;S61;S36/S37/S39
RIDADR UN 3077 9/PG 3
WGK Germany 3
RTECS DJ4200000
Packaging Group III
Hazard Class 6.1(b)

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title: CAS No. 192-97-2 | Chemsrc address: https://m.chemsrc.com/en/baike/520168.html

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