38274-54-3
38274-54-3 structure
- Name: Benurestat
- Chemical Name: 4-chloro-N-[2-(hydroxyamino)-2-oxoethyl]benzamide
- CAS Number: 38274-54-3
- Molecular Formula: C9H9ClN2O3
- Molecular Weight: 228.63200
- Catalog: Signaling Pathways Anti-infection Bacterial
- Create Date: 2018-09-14 10:58:02
- Modify Date: 2024-01-03 10:42:44
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Benurestat is an orally active urease inhibitor. Benurestat can be used for infected ureolysis research[1].
| Name | 4-chloro-N-[2-(hydroxyamino)-2-oxoethyl]benzamide |
|---|---|
| Synonyms |
EU-2826
Benurstat Benurestat |
| Description | Benurestat is an orally active urease inhibitor. Benurestat can be used for infected ureolysis research[1]. |
|---|---|
| Related Catalog | |
| In Vivo | Benurestat administration, 25 mg/kg, 50 mg/kg, or 100 mg/kg, causes a decrease in the urinary excretion of ammonia from rats with experimental P. mirabilis genitourinary tract infection[1]. The number of viable bacteria present in the bladders of infected rats is significantly less after the administration of Benurestat plus Nitrofurantoin, Sulfamethoxazole, or Ampicillin than the respective numbers that are obtained from control infected rats or from rats administered either component of the combination separately[1]. |
| References |
| Density | 1.414g/cm3 |
|---|---|
| Molecular Formula | C9H9ClN2O3 |
| Molecular Weight | 228.63200 |
| Exact Mass | 228.03000 |
| PSA | 78.43000 |
| LogP | 1.35700 |
| Index of Refraction | 1.59 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATAMUTATION DATA
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| Hazard Codes | Xi |
|---|---|
| HS Code | 2924299090 |
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~%
38274-54-3 |
| Literature: Munakata; Tanaka; Toyoshima Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 7 p. 2045 - 2051 |
|
~%
38274-54-3 |
| Literature: Munakata; Tanaka; Toyoshima Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 7 p. 2045 - 2051 |
|
~%
38274-54-3 |
| Literature: Munakata; Tanaka; Toyoshima Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 7 p. 2045 - 2051 |
| Precursor 3 | |
|---|---|
| DownStream 0 | |
| HS Code | 2924299090 |
|---|---|
| Summary | 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |