- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Mal-C6-amine TFA
- Price:
- Purity: 98.0%
- Stocking Period: 10 Day
- Contact: Yang
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Mal-C6-amine TFA
- Price: ￥508.0/25mg ￥1218.0/100mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: Mal-C6-amine TFA
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: 1-(6-AMINOHEXYL)-1H-PYRROLE-2,5-DIONE 2,2,2-TRIFLUOROACETATE
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
731862-92-3
731862-92-3 structure
- Name: Mal-C6-amine TFA
- Chemical Name: 1-(6-Aminohexyl)-1H-pyrrole-2,5-dione 2,2,2-trifluoroacetate
- CAS Number: 731862-92-3
- Molecular Formula: C12H17F3N2O4
- Molecular Weight: 310.270
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-11-24 10:20:05
- Modify Date: 2024-01-11 17:52:26
-
Mal-C6-amine (TFA) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 1-(6-Aminohexyl)-1H-pyrrole-2,5-dione 2,2,2-trifluoroacetate |
|---|---|
| Synonyms |
1-(6-aminohexyl)pyrrole-2,5-dione,2,2,2-trifluoroacetic acid
1-(6-Aminohexyl)-1H-pyrrole-2,5-dione trifluoroacetate (1:1) Acetic acid, 2,2,2-trifluoro-, compd. with 1-(6-aminohexyl)-1H-pyrrole-2,5-dione (1:1) |
| Description | Mal-C6-amine (TFA) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
Alkyl-Chain |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C12H17F3N2O4 |
|---|---|
| Molecular Weight | 310.270 |
| Exact Mass | 310.114044 |
| PSA | 100.70000 |
| LogP | 1.70200 |
| Hazard Codes | Xi |
|---|---|
| HS Code | 2925190090 |
| HS Code | 2925190090 |
|---|---|
| Summary | 2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |