Shanghai Nianxing Industrial Co., Ltd
China
Product Name: OU749
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Purity: 98.0%
Stocking Period: 10 Day
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519170-13-9

519170-13-9 structure

519170-13-9 structure

Name: OU749
Chemical Name: N-[5-[(4-methoxyphenyl)methyl]-1,3,4-thiadiazol-2-yl]benzenesulfonamide
CAS Number: 519170-13-9
Molecular Formula: C₁₆H₁₅N₃O₃S₂
Molecular Weight: 361.44
Catalog: Research Areas Cancer
Create Date: 2017-04-02 23:34:37
Modify Date: 2024-01-07 23:20:56
OU749 is a potent γ-glutamyl transpeptidase (GGT) inhibitor with a Ki value of 17.6 µM. OU749 shows cytotoxicity[1].

Name	N-[5-[(4-methoxyphenyl)methyl]-1,3,4-thiadiazol-2-yl]benzenesulfonamide
Synonyms	Benzenesulfonamide, N-[5-[(4-methoxyphenyl)methyl]-1,3,4-thiadiazol-2-yl]- N-[5-(4-Methoxybenzyl)-1,3,4-thiadiazol-2-yl]benzenesulfonamide OU749

Description	OU749 is a potent γ-glutamyl transpeptidase (GGT) inhibitor with a Ki value of 17.6 µM. OU749 shows cytotoxicity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
Target	Ki: 17.6 µM (GGT)[1]
References	[1]. King JB, et al. A novel, species-specific class of uncompetitive inhibitors of gamma-glutamyl transpeptidase. J Biol Chem. 2009 Apr 3;284(14):9059-65.

Density	1.4±0.1 g/cm3
Boiling Point	565.6±52.0 °C at 760 mmHg
Molecular Formula	C₁₆H₁₅N₃O₃S₂
Molecular Weight	361.44
Flash Point	295.9±30.7 °C
Exact Mass	361.055481
PSA	117.80000
LogP	3.04
Vapour Pressure	0.0±1.5 mmHg at 25°C
Index of Refraction	1.644

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
RIDADR	NONH for all modes of transport

98-09-9 structure

98-09-9

63617-18-5 structure

63617-18-5

~41%

519170-13-9 structure

519170-13-9

Literature: Wickham, Stephanie; Regan, Nicholas; West, Matthew B.; Kumar, Vidya Prasanna; Thai, Justin; Li, Pui Kai; Cook, Paul F.; Hanigan, Marie H. Journal of Enzyme Inhibition and Medicinal Chemistry, 2012 , vol. 27, # 4 p. 476 - 489

104-01-8 structure

104-01-8

~%

519170-13-9 structure

519170-13-9

Literature: Wickham, Stephanie; Regan, Nicholas; West, Matthew B.; Kumar, Vidya Prasanna; Thai, Justin; Li, Pui Kai; Cook, Paul F.; Hanigan, Marie H. Journal of Enzyme Inhibition and Medicinal Chemistry, 2012 , vol. 27, # 4 p. 476 - 489

Precursor 3
98-09-9 63617-18-5 104-01-8
DownStream 0

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