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66441-23-4

66441-23-4 structure
66441-23-4 structure

Name fenoxaprop-ethyl
Synonyms Ethyl 2-{4-[(6-chlorobenzoxazol-2-yl)oxy]phenoxy}propionate
ethyl (RS)-2-[4-(6-chloro-1,3-benzoxazol-2-yloxy)phenoxy]propionate
ethyl 2-[4-[(6-chloro-2-benzoxazolyl)oxy]phenoxy]propanoate
EINECS 266-362-9
MFCD00078610
rac-ethyl (2R)-2-{4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy}propanoate
ethyl (RS)-2-[4-(6-chlorobenzoxazol-2-yloxy)phenoxy]propionate
Fenoxaprop-ethyl
Density 1.31g/cm3
Boiling Point 477.5ºC at 760mmHg
Melting Point 84-85ºC
Molecular Formula C18H16ClNO5
Molecular Weight 361.77600
Flash Point 242.6ºC
Exact Mass 361.07200
PSA 70.79000
LogP 4.60390
Index of Refraction 1.587
Storage condition -20°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UA2454000
CHEMICAL NAME :
Propanoic acid, 2-(4-((6-chloro-2-benzoxazolyl)oxy)phenoxy)-, ethyl ester, (+-)-
CAS REGISTRY NUMBER :
66441-23-4
LAST UPDATED :
199710
DATA ITEMS CITED :
11
MOLECULAR FORMULA :
C18-H16-Cl-N-O5
MOLECULAR WEIGHT :
361.80

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2357 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,373,1991
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>510 mg/m3
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 17,S17,1992
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,373,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
739 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989 Volume(issue)/page/year: 11,625,1989
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4670 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,373,1991
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PBCWDF Proceedings of the British Crop Protection Conference - Weeds. (British Crop Protection Council, 2A Kidderminster Rd., Croydon, CRO 2UE, UK) 1976- Volume(issue)/page/year: -,11,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C136,1991
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
511 mg/m3/4H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C136,1991 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
605 mg/kg/32D-C
TOXIC EFFECTS :
Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases Biochemical - Metabolism (Intermediary) - lipids including transport
REFERENCE :
NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 17,S17,1992
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1210 mg/kg/32D-C
TOXIC EFFECTS :
Liver - hepatitis (hepatocellular necrosis), diffuse Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases
REFERENCE :
NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 17,S17,1992
Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning
Hazard Statements H317-H410
Precautionary Statements P273-P280-P501
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xi,N
Risk Phrases R43;R50/53
Safety Phrases S24;S37;S60;S61
RIDADR UN 3077 9/PG 3
RTECS UA2454000
HS Code 2934999023

~85%

66441-23-4 structure

66441-23-4

Literature: Kalhor, Mehdi; Dadras, Akbar; Mobinikhaledi, Akbar; Tajik, Hassan Journal of the Chilean Chemical Society, 2011 , vol. 56, # 4 p. 833 - 836

~88%

66441-23-4 structure

66441-23-4

Literature: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY Patent: WO2004/2925 A2, 2004 ; Location in patent: Page 12 ;

~86%

66441-23-4 structure

66441-23-4

Literature: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY Patent: WO2004/2925 A2, 2004 ; Location in patent: Page 12 ;

~62%

66441-23-4 structure

66441-23-4

Literature: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY Patent: WO2004/2925 A2, 2004 ; Location in patent: Page 19 ;

~91%

66441-23-4 structure

66441-23-4

Literature: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY Patent: WO2004/2925 A2, 2004 ; Location in patent: Page 11 ;
HS Code 2934999023
Summary 2934999023 2,8,9-trioxa-5-aza-1-silabicyclo[3.3.3]undecane。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:20.0%