Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1-(2-DEOXY-2-FLUORO-B-D-ARABINOFURANOSYL)URACIL
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Purity: 98.0%
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69123-94-0

69123-94-0 structure

Name: 2'-Deoxy-2'-fluorouridine
Chemical Name: 1-(2-Deoxy-2-fluoro-b-D-arabinofuranosyl)uracil
CAS Number: 69123-94-0
Molecular Formula: C₉H₁₁FN₂O₅
Molecular Weight: 246.19
Catalog: Biochemical Carbohydrate Monosaccharide
Create Date: 2018-12-26 13:51:48
Modify Date: 2026-08-01 23:03:23
1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	1-(2-Deoxy-2-fluoro-b-D-arabinofuranosyl)uracil
Synonyms	1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-2,4(1H,3H)-pyrimidinedione 2’-Deoxy-2’-fluoro-b-D-abinouridine, antiviral anticancer agent 2'-Fluoro-2'-deoxy-abinofuranosyl-uridine 2'-Fluoro-2'-deoxy-β-Dabino-furanosyluridine 2’-Deoxy-2’-fluoro-beta-D-abinouridine 2'-Deoxy-2'-fluoro-beta-D-abinouridine 1-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione 2,4(1H,3H)-PYRIMIDINEDIONE, 1-(2-DEOXY-2-FLUORO-BETA-D-ABINOFURANOSYL) 1-((2R,3S,4R,5R)-3-FLUORO-4-HYDROXY-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-2-YL)-1H-PYRIMIDINE-2,4-DIONE 2'-Fluoro-2'-deoxy-β-D-abino-furanosyluridine 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-2-fluoro-β-D-abinofuranosyl) 2'-Fluoro-2'-deoxy-abino-Uridine 1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione 2'-FLUORO 2'-DEOXYURACIL-BETA-D-ABINOFURANOSIDE 2'-Fluoro-abinofuranosyl-2'-deoxy-uridine 1-(2'-Deoxy-2'-fluoro-b-D-abinofuranosyl)uracil 1,3-Dimethyl-4-Amino-5-Formamide-Uracil FAU 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)pyrimidine-2,4(1H,3H)-dione 2’-fluoro-5-ethyl-1-beta-d-abinofuranosyluracil antiviral anticancer agent 2’-Deoxy-2’-fluoro-β-D-abinouridine 1-[(2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione 2'-Fluoro-2'-deoxyuridine 2'-Deoxy-2'-fluoro-D-abinouridine 1-(2-deoxy-2-fluoro-beta-d-abinofuranosyl)-uraci 2’-Deoxy-2’-fluoro-b-D-abinouridine 1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione 2'-FLUORO-2'-DEOXYURACYL-BETA-D-ABINOFURANOSIDE 1-(2-Deoxy-2-fluoro-beta-D-abinofuranosyl)uracil 2-Deoxy-2'-fluoro-β-D-abinouridine a-2'-F-2'-dU 1-(2-Deoxy-2-fluoro-β-D-abinofuranosyl)uracil 2,4(1H,3H)-PyriMidinedione, 1-(2-deoxy-2-fluoro-b-D-abinofuranosyl) 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)uracil 2'-FANA-uridine

Description	1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Density	1.6±0.1 g/cm3
Molecular Formula	C₉H₁₁FN₂O₅
Molecular Weight	246.19
Exact Mass	246.065201
PSA	104.55000
LogP	-1.31
Index of Refraction	1.608
Storage condition	2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YQ9512000

CHEMICAL NAME :: Uracil, 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-

CAS REGISTRY NUMBER :: 69123-94-0

LAST UPDATED :: 198708

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C11-H15-F-N2-O5

MOLECULAR WEIGHT :: 274.28

WISWESSER LINE NOTATION :: T6NVMVJ E2 A- BT5OTJ CF DQ E1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Rodent - rat Bone marrow

DOSE/DURATION :: 3700 umol/L

REFERENCE :: PAACA3 Proceedings of the American Association for Cancer Research. (Waverly Press, 428 E. Preston St., Baltimore, MD 21202) V.1- 1954- Volume(issue)/page/year: 26,333,1985

HS Code	2934999090

Precursor 0
DownStream 2
66-22-8 122757-52-2

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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