173534-37-7

173534-37-7 structure

Name: S-4048
Chemical Name: (1S,3R,4R,5R)-1-{[(1R,2S)-2-(4-Chlorophenyl)cyclopropyl]methoxy}- 3,4-dihydroxy-5-{[(2Z)-3-(1H-imidazo[4,5-b]pyridin-1-yl)-3-phenyl -2-propenoyl]oxy}cyclohexanecarboxylic acid
CAS Number: 173534-37-7
Molecular Formula: C₃₂H₃₀ClN₃O₇
Molecular Weight: 604.04900
Catalog: Research Areas Metabolic Disease
Create Date: 2016-07-17 21:26:54
Modify Date: 2025-08-16 16:57:49
S-4048 is a Glucose-6-phosphatase (G6Pase) inhibitor with an IC50 value of 9.4 nM for rat microsomes.

Name	(1S,3R,4R,5R)-1-{[(1R,2S)-2-(4-Chlorophenyl)cyclopropyl]methoxy}- 3,4-dihydroxy-5-{[(2Z)-3-(1H-imidazo[4,5-b]pyridin-1-yl)-3-phenyl -2-propenoyl]oxy}cyclohexanecarboxylic acid

Description	S-4048 is a Glucose-6-phosphatase (G6Pase) inhibitor with an IC50 value of 9.4 nM for rat microsomes.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
Target	IC50：9.4 nM for rat microsomes.
References	[1]. By Parker, Janice C, et al. Plasma glucose levels are reduced in rats and mice treated with an inhibitor of glucose-6-phosphate translocase. Diabetes (1998), 47(10), 1630-1636.