Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Desmethylbellidifolin
Price: ￥2948.0/10mg
Purity: 98.0%
Stocking Period: 2 Day
Contact: Liu jia

2980-32-7

2980-32-7 structure

2980-32-7 structure

Name: Desmethylbellidifolin
Chemical Name: bellidin
CAS Number: 2980-32-7
Molecular Formula: C₁₃H₈O₆
Molecular Weight: 260.199
Catalog: Biochemical Plant extracts
Create Date: 2018-07-21 08:44:12
Modify Date: 2024-01-08 09:28:21
1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) is a natural xanthone extracted from Gentianella acuta. 1,3,5,8-Tetrahydroxyxanthone has antispasmodic effect and anti-inflammatory activity[1].

Name	bellidin
Synonyms	Demethylbellidifolin Xanthen-9-one,1,3,5,8-tetrahydroxy Desmethylbellidifolin Bellidin norbellidifolin 1,3,5,8-tetrahydroxyxanthone Desmethybellidifolin norbellidifodin 1,3,5,8-Tetrahydroxy-9H-xanthen-9-one 9H-Xanthen-9-one, 1,3,5,8-tetrahydroxy- 1,3,5,8-tetrahydroxy-xanthen-9-one 1,3,5,8-tetrahydroxyxanthen-9-one

Description	1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) is a natural xanthone extracted from Gentianella acuta. 1,3,5,8-Tetrahydroxyxanthone has antispasmodic effect and anti-inflammatory activity[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease
In Vitro	1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) attenuates lipopolysaccharide-induced nitric oxide release and proinflammatory cytokine expression in RAW264.7 cells[1].
In Vivo	1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin; orally; 5, 10, 20 mg/kg; 12 days) can inhibit trinitrobenzenesulfonic acid (TNBS)-induced ulcerative colitis (UC), reducing inflammatory response and alleviate colon muscle spasm[1].
References	[1]. Ni Y, et al. Desmethylbellidifolin From Gentianella acuta Ameliorate TNBS-Induced Ulcerative Colitis Through Antispasmodic Effect and Anti-Inflammation. Front Pharmacol. 2019 Sep 20;10:1104.

Density	1.8±0.1 g/cm3
Boiling Point	605.6±55.0 °C at 760 mmHg
Melting Point	317ºC
Molecular Formula	C₁₃H₈O₆
Molecular Weight	260.199
Flash Point	242.0±25.0 °C
Exact Mass	260.032074
PSA	111.13000
LogP	0.33
Vapour Pressure	0.0±1.8 mmHg at 25°C
Index of Refraction	1.801

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ZD6122300

CHEMICAL NAME :: Xanthen-9-one, 1,3,5,8-tetrahydroxy-

CAS REGISTRY NUMBER :: 2980-32-7

BEILSTEIN REFERENCE NO. :: 0286545

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C13-H8-O6

MOLECULAR WEIGHT :: 260.21

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 20 ug/plate

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 150,141,1985

Precursor 9
103726-10-9 103726-21-2 103726-17-6 2798-25-6
108-73-6 22248-13-1 60241-74-9 5653-53-2
25245-34-5
DownStream 3
49599-09-9 521-65-3 103726-10-9