126100-97-8

126100-97-8 structure

Name: Dimiracetam
Chemical Name: 3,6,7,7a-tetrahydro-1H-pyrrolo[1,2-a]imidazole-2,5-dione
CAS Number: 126100-97-8
Molecular Formula: C₆H₈N₂O₂
Molecular Weight: 140.14
Catalog: Research Areas Cancer
Create Date: 2018-08-09 13:01:30
Modify Date: 2024-01-06 18:06:45
Dimiracetam is an orally active compound, with anti-neuropathic activity. Dimiracetam inhibits hypersensitivity and neurological alterations, and inhibits Sorafenib (HY-10201)-induced neuropathy in cold stimulation rat models[1].

Name	3,6,7,7a-tetrahydro-1H-pyrrolo[1,2-a]imidazole-2,5-dione
Synonyms	2,5-dioxohexahydro-1H-pyrrolo[1,2-a]imidazole tetrahydro-pyrrolo[1,2-a]imidazole-2,5-dione dimiracetam 1H-Pyrrolo(1,2-a)imidazole-2,5(3H,6H)-dione,dihydro (+-)-Dihydro-1H-pyrrolo(1,2-a)imidazole-2,5(3H,6H)-dione Dimiracetam [INN]

Description	Dimiracetam is an orally active compound, with anti-neuropathic activity. Dimiracetam inhibits hypersensitivity and neurological alterations, and inhibits Sorafenib (HY-10201)-induced neuropathy in cold stimulation rat models[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Di Cesare Mannelli L, et al. A model of neuropathic pain induced by sorafenib in the rat: Effect of dimiracetam. Neurotoxicology. 2015 Sep;50:101-7. [2]. Di Cesare Mannelli L, et al. A rat model of FOLFOX-induced neuropathy: effects of oral dimiracetam in comparison with duloxetine and pregabalin. Cancer Chemother Pharmacol. 2017 Dec;80(6):1091-1103.

153393-25-0

~82%

126100-97-8

Literature: Journal of Medicinal Chemistry, , vol. 36, # 26 p. 4214 - 4220

1668-10-6

126101-13-1

~22%

126100-97-8

Literature: Journal of Medicinal Chemistry, , vol. 36, # 26 p. 4214 - 4220

Precursor 1
1668-10-6
DownStream 0