Dimiracetam

Modify Date: 2024-01-06 18:06:45

Dimiracetam Structure
Dimiracetam structure
Common Name Dimiracetam
CAS Number 126100-97-8 Molecular Weight 140.14
Density 1.4g/cm3 Boiling Point 460.5ºC at 760 mmHg
Molecular Formula C6H8N2O2 Melting Point N/A
MSDS N/A Flash Point 232.3ºC

 Use of Dimiracetam


Dimiracetam is an orally active compound, with anti-neuropathic activity. Dimiracetam inhibits hypersensitivity and neurological alterations, and inhibits Sorafenib (HY-10201)-induced neuropathy in cold stimulation rat models[1].

 Names

Name 3,6,7,7a-tetrahydro-1H-pyrrolo[1,2-a]imidazole-2,5-dione
Synonym More Synonyms

 Dimiracetam Biological Activity

Description Dimiracetam is an orally active compound, with anti-neuropathic activity. Dimiracetam inhibits hypersensitivity and neurological alterations, and inhibits Sorafenib (HY-10201)-induced neuropathy in cold stimulation rat models[1].
Related Catalog
References

[1]. Di Cesare Mannelli L, et al. A model of neuropathic pain induced by sorafenib in the rat: Effect of dimiracetam. Neurotoxicology. 2015 Sep;50:101-7.  

[2]. Di Cesare Mannelli L, et al. A rat model of FOLFOX-induced neuropathy: effects of oral dimiracetam in comparison with duloxetine and pregabalin. Cancer Chemother Pharmacol. 2017 Dec;80(6):1091-1103.  

 Chemical & Physical Properties

Density 1.4g/cm3
Boiling Point 460.5ºC at 760 mmHg
Molecular Formula C6H8N2O2
Molecular Weight 140.14
Flash Point 232.3ºC
Exact Mass 140.05900
PSA 52.90000
Vapour Pressure 1.16E-08mmHg at 25°C
Index of Refraction 1.585

 Precursor & DownStream

Precursor  1

DownStream  0

 Synonyms

2,5-dioxohexahydro-1H-pyrrolo[1,2-a]imidazole
tetrahydro-pyrrolo[1,2-a]imidazole-2,5-dione
dimiracetam
1H-Pyrrolo(1,2-a)imidazole-2,5(3H,6H)-dione,dihydro
(+-)-Dihydro-1H-pyrrolo(1,2-a)imidazole-2,5(3H,6H)-dione
Dimiracetam [INN]