13048-95-8

13048-95-8 structure

Name: N(4), O(2')-dimethylcytidine
Chemical Name: 1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-4-(methylamino)pyrimidin-2-one
CAS Number: 13048-95-8
Molecular Formula: C₁₁H₁₇N₃O₅
Molecular Weight: 271.27
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2016-03-26 11:48:09
Modify Date: 2024-01-02 11:14:52
N4-Methyl-2’-O-methyl-cytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-4-(methylamino)pyrimidin-2-one
Synonyms	N,2'-O-Dimethylcytidine Cytidine,N-methyl-2'-O-methyl N4,O2'-Dimethylcytidin N4,2'-O-dimethylcytidine N4-Methyl-2'-O-methyl-cytidin N4,O2'-dimethyl-cytidine

Description	N4-Methyl-2’-O-methyl-cytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Hazard Codes	Xn

1085342-83-1

~98%

13048-95-8

Literature: Mahto, Santosh K.; Chow, Christine S. Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 19 p. 8795 - 8800

110588-51-7

~92%

13048-95-8

Literature: Nyilas, A.; Chattopadhyaya, J. Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1986 , vol. 40, # 10 p. 826 - 830

108782-90-7

13048-95-8

Literature: Nyilas, A.; Chattopadhyaya, J. Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1986 , vol. 40, # 10 p. 826 - 830

110567-19-6

13048-95-8

Literature: Nyilas, A.; Chattopadhyaya, J. Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1986 , vol. 40, # 10 p. 826 - 830

415903-48-9

13048-95-8

Literature: Nyilas, A.; Chattopadhyaya, J. Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1986 , vol. 40, # 10 p. 826 - 830

58-96-8

13048-95-8

Literature: Nyilas, A.; Chattopadhyaya, J. Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1986 , vol. 40, # 10 p. 826 - 830

69304-38-7

13048-95-8

Literature: Nyilas, A.; Chattopadhyaya, J. Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1986 , vol. 40, # 10 p. 826 - 830