139115-90-5

139115-90-5 structure

Name: Azido-PEG2-alcohol
Chemical Name: 2-(2-azidoethoxy)ethanol
CAS Number: 139115-90-5
Molecular Formula: C₄H₉N₃O₂
Molecular Weight: 131.13300
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2016-02-12 10:18:39
Modify Date: 2026-07-01 18:05:56
Azido-PEG2-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	2-(2-azidoethoxy)ethanol
Synonyms	Ethanol,2-(2-azidoethoxy) Ethanol, 2-(2-azidoethoxy) Azido-PEG2 Azido-PEG2-Alchol (2-azidoethoxy)ethanol Azido-PEG2-OH 5-azido-3-oxapentanol 2-(2-Azidoethoxy)ethanol AZIDO-PEG2-HYDROXY N3-PEG2-OH,Azido-PEG2-alcohol,AZIDO-PEG2-HYDROXY 5-azido-3-oxa-1-pentanol 2-(2-Azidoethoxy)ethan-1-ol 2-(2-azidoethoxy)-ethanol N3-PEG2-OH Azido - PEG1 Azide polyethylene glycol 2-(2-azidoethoxy)ethan-1-ol

Description	Azido-PEG2-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562