1415559-43-1

1415559-43-1 structure

Name: CDK9-IN-1
Chemical Name: N-[5-[[6-[3-(1,3-dioxoisoindol-2-yl)phenyl]pyrimidin-4-yl]amino]-2-methylphenyl]methanesulfonamide
CAS Number: 1415559-43-1
Molecular Formula: C₂₆H₂₁N₅O₄S
Molecular Weight: 499.54100
Catalog: Signaling Pathways Anti-infection HIV
Create Date: 2016-03-22 09:10:51
Modify Date: 2024-01-14 20:09:51
CDK9-IN-1 is a novel, selective CDK9 inhibitor for the treatment of HIV infection, with an IC50 of 39 nM for CDK9/CycT1, extracted from reference, compound 87.

Name	N-[5-[[6-[3-(1,3-dioxoisoindol-2-yl)phenyl]pyrimidin-4-yl]amino]-2-methylphenyl]methanesulfonamide
Synonyms	CS-0456 CDK9 inhibitor CDK9-IN-1

Description	CDK9-IN-1 is a novel, selective CDK9 inhibitor for the treatment of HIV infection, with an IC50 of 39 nM for CDK9/CycT1, extracted from reference, compound 87.
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection
Target	CDK9/CycT1:39 nM (IC50)
In Vitro	CDK9-IN-1 is a potent CDK9 inhibitor that shows high activity against HIV-1 replication[1].
References	[1]. Nemeth G, et al. Novel, selective CDK9 inhibitors for the treatment of HIV infection. Curr Med Chem. 2011;18(3):342-358.