CDK9-IN-1

Modify Date: 2024-01-14 20:09:51

CDK9-IN-1 Structure
CDK9-IN-1 structure
Common Name CDK9-IN-1
CAS Number 1415559-43-1 Molecular Weight 499.54100
Density N/A Boiling Point N/A
Molecular Formula C26H21N5O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CDK9-IN-1


CDK9-IN-1 is a novel, selective CDK9 inhibitor for the treatment of HIV infection, with an IC50 of 39 nM for CDK9/CycT1, extracted from reference, compound 87.

 Names

Name N-[5-[[6-[3-(1,3-dioxoisoindol-2-yl)phenyl]pyrimidin-4-yl]amino]-2-methylphenyl]methanesulfonamide
Synonym More Synonyms

 CDK9-IN-1 Biological Activity

Description CDK9-IN-1 is a novel, selective CDK9 inhibitor for the treatment of HIV infection, with an IC50 of 39 nM for CDK9/CycT1, extracted from reference, compound 87.
Related Catalog
Target

CDK9/CycT1:39 nM (IC50)

In Vitro CDK9-IN-1 is a potent CDK9 inhibitor that shows high activity against HIV-1 replication[1].
References

[1]. Nemeth G, et al. Novel, selective CDK9 inhibitors for the treatment of HIV infection. Curr Med Chem. 2011;18(3):342-358.

 Chemical & Physical Properties

Molecular Formula C26H21N5O4S
Molecular Weight 499.54100
Exact Mass 499.13100
PSA 129.74000
LogP 5.65950
Storage condition 2-8℃

 Synonyms

CS-0456
CDK9 inhibitor
CDK9-IN-1
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