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152305-87-8

152305-87-8 structure
152305-87-8 structure
  • Name: sulfo-NHS-acetate
  • Chemical Name: 1-acetyloxy-2,5-dioxopyrrolidine-3-sulfonic acid
  • CAS Number: 152305-87-8
  • Molecular Formula: C6H7NO7S
  • Molecular Weight: 237.18700
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-12-19 12:47:31
  • Modify Date: 2024-01-14 17:19:56
  • Sulfo-NHS-Acetate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 1-acetyloxy-2,5-dioxopyrrolidine-3-sulfonic acid
Synonyms Sulfo-nhs-acetate
BIM103
Sulfosuccinimidyl acetate
3-Pyrrolidinesulfonicacid,1-(acetyloxy)-2,5-dioxo
1-Acetoxy-2,5-dioxopyrrolidine-3-sulfonic acid
Description Sulfo-NHS-Acetate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.8g/cm3
Molecular Formula C6H7NO7S
Molecular Weight 237.18700
Exact Mass 236.99400
PSA 126.43000
Index of Refraction 1.583
Hazard Codes Xi
HS Code 2925190090
HS Code 2925190090
Summary 2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%