52187-80-1

52187-80-1 structure

Name: Luteolin-3',7-di-O-glucoside
Chemical Name: 5-hydroxy-2-[4-hydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one
CAS Number: 52187-80-1
Molecular Formula: C₂₇H₃₀O₁₆
Molecular Weight: 610.51700
Catalog: Research Areas Infection
Create Date: 2018-12-18 10:24:20
Modify Date: 2025-08-26 05:24:01
Luteolin-3′,7-diglucoside is a glycoside isolate from R. luteolin. Luteolin-3′,7-diglucoside significantly inhibits cataracts induced in ovine lenses. Luteolin-3′,7-diglucoside inhibits the activity of Ureaplasma urealyticumATCC and clinical strains[1][2][3].

Name	5-hydroxy-2-[4-hydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one
Synonyms	Luteolin-3',7-di-O-glucoside EINECS 257-724-7

Description	Luteolin-3′,7-diglucoside is a glycoside isolate from R. luteolin. Luteolin-3′,7-diglucoside significantly inhibits cataracts induced in ovine lenses. Luteolin-3′,7-diglucoside inhibits the activity of Ureaplasma urealyticumATCC and clinical strains[1][2][3].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Others >> Others
Target	ATCC and clinical strains of Ureaplasma urealyticum[3]
In Vitro	Luteolin-3′,7-diglucoside (10 µM；24 h) 显著抑制在 45 % 低渗肝素缓冲溶液 (HBS) 中孵育 24 h 诱发的绵羊晶状体白内障[2]。 Luteolin-3′,7-diglucoside 抑制解脲支原体 ATCC 菌株的活性 (MIC=7.8-15.6 µM) 和解脲支原体临床菌株的活性 (MIC=0.48-1.95 µM)[3]。
References	[1]. Cristea D, et al. Identification and quantitative HPLC analysis of the main flavonoids present in weld (Reseda luteola L.)[J]. Dyes and Pigments, 2003, 57(3): 267-272. [2]. Vit P, et al. Putative anticataract properties of honey studied by the action of flavonoids on a lens culture model[J]. Journal of Health Science, 2008, 54(2): 196-202. [3]. Bisignano C, et al. In Vitro Efficacy of Crataegus oxycantha L.(Hawthorn) and Its Major Components against ATCC and Clinical Strains of Ureaplasma urealyticum[J]. Advances in Microbiology, 2016, 6(12): 909-916.