37827-06-8

37827-06-8 structure

Name: (Sar1,Ile8)-Angiotensin II
Chemical Name: sar-arg-val-tyr-ile-his-pro-ile
CAS Number: 37827-06-8
Molecular Formula: C₄₆H₇₃N₁₃O₁₀
Molecular Weight: 968.153
Catalog: Peptides
Create Date: 2016-02-17 10:51:46
Modify Date: 2024-01-10 21:01:54
[Sar1, Ile8]-Angiotensin II is a peptide that has multiple effects on vascular smooth muscle, including contraction of normal arteries and hypertrophy or hyperplasia of cultured cells or diseased vessels.

Name	sar-arg-val-tyr-ile-his-pro-ile
Synonyms	Sarile N-Methylglycyl-N-(diaminomethylene)-L-ornithyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-isoleucine <Sar1,Ile5,Ile8>-angiotensin II <Sar1-Ile8>-angiotensin II SARILESIN N-methylglycyl-N-(diaminomethylidene)-L-ornithyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-isoleucine L-isoleucine, N-methylglycyl-N-(diaminomethylene)-L-ornithyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl- Angiotensin II [Sar1 Ile8] [Sar1, Ile8]-Angiotensin II

Description	[Sar1, Ile8]-Angiotensin II is a peptide that has multiple effects on vascular smooth muscle, including contraction of normal arteries and hypertrophy or hyperplasia of cultured cells or diseased vessels.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Angiotensin Receptor Peptides Research Areas >> Cardiovascular Disease
In Vitro	Angiotensin II has multiple effects on vascular smooth muscle, including contraction of normal arteries and hypertrophy or hyperplasia of cultured cells or diseased vessels. Angiotensin II activates both the NADPH and NADH oxidases, and stimulates superoxide anion formation in vascular smooth muscle cells[1].
References	[1]. Griendling KK, et al. Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ Res. 1994 Jun;74(6):1141-8.