(Sar1,Ile8)-Angiotensin II

Modify Date: 2025-08-23 10:16:51

(Sar1,Ile8)-Angiotensin II Structure
(Sar1,Ile8)-Angiotensin II structure
Common Name (Sar1,Ile8)-Angiotensin II
CAS Number 37827-06-8 Molecular Weight 968.153
Density 1.4±0.1 g/cm3 Boiling Point N/A
Molecular Formula C46H73N13O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (Sar1,Ile8)-Angiotensin II


[Sar1, Ile8]-Angiotensin II is a peptide that has multiple effects on vascular smooth muscle, including contraction of normal arteries and hypertrophy or hyperplasia of cultured cells or diseased vessels.

 Names

Name sar-arg-val-tyr-ile-his-pro-ile
Synonym More Synonyms

 (Sar1,Ile8)-Angiotensin II Biological Activity

Description [Sar1, Ile8]-Angiotensin II is a peptide that has multiple effects on vascular smooth muscle, including contraction of normal arteries and hypertrophy or hyperplasia of cultured cells or diseased vessels.
Related Catalog
In Vitro Angiotensin II has multiple effects on vascular smooth muscle, including contraction of normal arteries and hypertrophy or hyperplasia of cultured cells or diseased vessels. Angiotensin II activates both the NADPH and NADH oxidases, and stimulates superoxide anion formation in vascular smooth muscle cells[1].
References

[1]. Griendling KK, et al. Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ Res. 1994 Jun;74(6):1141-8.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Molecular Formula C46H73N13O10
Molecular Weight 968.153
Exact Mass 967.560364
PSA 355.05000
LogP 1.67
Index of Refraction 1.638

 Synonyms

Sarile
N-Methylglycyl-N-(diaminomethylene)-L-ornithyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-isoleucine
<Sar1,Ile5,Ile8>-angiotensin II
<Sar1-Ile8>-angiotensin II
SARILESIN
N-methylglycyl-N-(diaminomethylidene)-L-ornithyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-isoleucine
L-isoleucine, N-methylglycyl-N-(diaminomethylene)-L-ornithyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-
Angiotensin II [Sar1 Ile8]
[Sar1, Ile8]-Angiotensin II
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