756526-03-1

756526-03-1 structure

Name: Bis-PEG5-NHS ester
Chemical Name: (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[3-(2,5-dioxopyrrolidin-1-yl)oxy-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
CAS Number: 756526-03-1
Molecular Formula: C₂₂H₃₂N₂O₁₃
Molecular Weight: 532.49500
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2018-12-25 13:22:59
Modify Date: 2024-01-10 15:40:58
Bis-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name	(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[3-(2,5-dioxopyrrolidin-1-yl)oxy-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
Synonyms	Bis-PEG5-NHS ester AmbotzPEG1435 BIS-SUCCINIMIDYL-4,7,10,13,16-PENTAOXANONADECANE-1,19-DIOATE B3728 Bis-dPEG5-NHS ester

Description	Bis-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References	[1]. Hans-Georg Lerchen, et al. Prodrugs of cytotoxic active agents having enzymatically cleavable groups. WO2018114798A1.