757220-04-5

757220-04-5 structure

Name: Di(N-desethyl) Amiodarone Hydrochloride
Chemical Name: [4-(2-aminoethoxy)-3,5-diiodophenyl]-(2-butyl-1-benzofuran-3-yl)methanone,hydrochloride
CAS Number: 757220-04-5
Molecular Formula: C₂₁H₂₂ClI₂NO₃
Molecular Weight: 625.67
Catalog: Signaling Pathways Autophagy Autophagy
Create Date: 2017-05-08 08:04:04
Modify Date: 2025-08-25 14:28:06
Di-N-desethyl Amiodarone hydrochloride is a metabolite of Amiodarone (HY-14187). Di-N-desethyl Amiodarone hydrochloride is a strong inhibitor of the respiratory chain[1].

Name	[4-(2-aminoethoxy)-3,5-diiodophenyl]-(2-butyl-1-benzofuran-3-yl)methanone,hydrochloride
Synonyms	Amiodarone Impurity 9

Description	Di-N-desethyl Amiodarone hydrochloride is a metabolite of Amiodarone (HY-14187). Di-N-desethyl Amiodarone hydrochloride is a strong inhibitor of the respiratory chain[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Autophagy >> Autophagy Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel
References	[1]. Anja Zahno,et al. The role of CYP3A4 in amiodarone-associated toxicity on HepG2cells. Biochem Pharmacol. 2011 Feb 1;81(3):432-41.